- Basic information
- CohesinDB ID: CDBP00420548
- Locus: chr21-42961474-42961813
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Data sourse: GSE67783
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Cell type: HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NANOG, ZNF207, POU5F1, RBBP5, SOX2, ZFX, SMAD3, WT1, ZNF770, DDX5, PRDM10, KDM1A, YY1, ETS1, SMAD2, RAD21, CHD7, MORC2, ATF2, MAX, GATA1, MED1, CREB1, CTCF, TCF12, SP1, BCL11A, EP300, TAF1, HDAC2, E2F6, ZBTB7A, CTBP2, BCOR, FOXP1, MAZ, TEAD4
- Target gene symbol (double-evidenced CRMs): CSTB,SLC37A1,PDXK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000160190,
ENSG00000160209,
ENSG00000160213,
- Related loop:
chr21:10325000-10350000~~chr21:42950000-42975000,
chr21:42575000-42600000~~chr21:42950000-42975000,
chr21:42936873-42938284~~chr21:42956494-42958234,
chr21:42950000-42975000~~chr21:43175000-43200000,
chr21:42950000-42975000~~chr21:43200000-43225000,
chr21:42950000-42975000~~chr21:43275000-43300000,
chr21:42950000-42975000~~chr21:43300000-43325000,
chr21:42950000-42975000~~chr21:43750000-43775000,
chr21:42954675-42957047~~chr21:42973040-42976308,