- Basic information
- CohesinDB ID: CDBP00420550
- Locus: chr21-42963590-42964529
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 81%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NCOA2, TRIM25, POU2F2, SMC1A, CHD8, TBL1X, MYCN, AGO1, KDM4C, ZFX, ZNF534, ZNF692, XBP1, ZBTB48, WT1, ZSCAN5A, TET2, ZNF770, CDK9, KDM1A, YY1, RELA, ZNF384, ATF3, AHR, MYC, ZNF362, SP140, GRHL3, HIF1A, ARNT, ATF4, SMC3, ZEB2, ZNF449, ZNF143, CDK8, RCOR1, DNMT3B, PLAG1, ZNF467, ARNTL, CEBPB, NCOA3, ZEB1, ZNF121, NR2F1, ZMYM3, LMO2, ESR1, OCA2, TP53, FEZF1, ZNF334, USF2, CTCF, SPI1, BCL11A, GSPT2, AR, PAX8, HDAC2, RYBP, RBM25, HSF1, ZBTB26, HNRNPLL, BRD4, ZNF512B, BCOR, CLOCK, MAZ, TEAD4, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): SLC37A1,PDXK,CSTB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000160190,
ENSG00000160209,
ENSG00000160213,
- Related loop:
chr21:10325000-10350000~~chr21:42950000-42975000,
chr21:42575000-42600000~~chr21:42950000-42975000,
chr21:42950000-42975000~~chr21:43175000-43200000,
chr21:42950000-42975000~~chr21:43200000-43225000,
chr21:42950000-42975000~~chr21:43275000-43300000,
chr21:42950000-42975000~~chr21:43300000-43325000,
chr21:42950000-42975000~~chr21:43750000-43775000,