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Basic information

CohesinDB ID: CDBP00420555

Locus: chr21-42978524-42979165

Data sourse: GSE67783, ENCSR153HNT

Cell type: K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 71%, "4_Tx": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOSL1, SOX2, XBP1, PATZ1, FOXA1, SUZ12, RBFOX2, LEO1, HDGF, ATF3, RUNX3, CHD7, MORC2, MECOM, ZNF189, PAX5, MZF1, ZSCAN4, ZNF467, ZNF629, ELF1, BCLAF1, TRIM28, ESR1, OCA2, ZFP91, CTCF, JUN, E2F6, PRDM4, IRF4, SOX6, ZNF528, EED, GLIS1, POU2F2, CHD8, BRD1, ZSCAN5D, POU5F1, ZNF263, MYCN, KDM4C, ZNF317, ZBTB17, ZBTB48, ZSCAN5A, STAT1, ZSCAN21, MLLT3, DDX5, NBN, ERG2, ERG, HOXC5, ASCL1, MYC, GRHL3, FOXK2, GABPA, PRDM14, ZNF398, TERF2, ZNF639, ARNTL, EZH2, SPI1, IRF1, KLF17, GATA2, MXD3, SIX2, FLI1, RELB, MRTFB, NCOA2, ZIM3, RUNX1, SMC1A, CEBPA, NKX2-2, ZNF335, ZFX, POU4F2, NFKBIA, ZNF534, ZNF770, TET2, PRDM10, CREBBP, ZNF384, NOTCH1, ZBTB2, RUNX2, CDK6, GATA4, OSR2, ARNT, PBX4, DAXX, NRF1, ZEB2, ZNF10, SUPT5H, CHD1, MED1, TEAD3, PML, ZXDB, SCRT2, U2AF1, SMAD1, KLF9, EVI1, RBM22, BCL11A, PHIP, BCOR, SMC3, MLLT1, STAG1, NFATC3, ZNF394, KLF13, MEF2B, FOXA2, EBF1, PAF1, ZNF600, ZNF692, GTF2B, WT1, ZNF30, ZSCAN16, ZNF574, ZBTB33, HOXB13, MPHOSPH8, KDM1A, YY1, RELA, TARDBP, NEUROD1, ZNF610, SP140, SKIL, HIF1A, OTX2, TAL1, MAX, ZNF143, AGO2, GATA1, PLAG1, SP7, NCOA3, NEUROG2, TP53, PKNOX1, ZBTB6, ELF3, TBX21, ARID4B, AR, ZNF324, ZNF366, ZBTB26, HSF1, SCRT1, BRD4, CLOCK, MAZ, ZSCAN23, AHR

Target gene symbol (double-evidenced CRMs): PKNOX1,SUMO3,UMODL1,DNMT3L,PFKL,UBE2G2,TRPM2,RRP1B,HSF2BP,CFAP410

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000177398, ENSG00000160199, ENSG00000160207, ENSG00000160208, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000184787, ENSG00000184900,

eachgene

Deatailed information for cohesin site CDBP00420555