- Basic information
- CohesinDB ID: CDBP00420560
- Locus: chr21-42984399-42985953
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Data sourse: GSE206145, GSE67783, ENCSR153HNT
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Cell type: K-562, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
83% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 76%,
"15_Quies": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, CHD8, MYCN, PAF1, ZFX, ZNF600, XBP1, WT1, ZBTB48, FOXA1, RUNX2, MYC, SUPT5H, TP53, OCA2, ZNF22, CTCF, RBM22, SPI1, ZNF257, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): UBE2G2,DNMT3L,TRPM2,PFKL,CFAP410,HSF2BP,UMODL1,RRP1B,PKNOX1,SUMO3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 10
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000177398,
ENSG00000160199,
ENSG00000160207,
ENSG00000160208,
ENSG00000142182,
ENSG00000141959,
ENSG00000160226,
ENSG00000142185,
ENSG00000184787,
ENSG00000184900,
- Related loop:
chr21:34350000-34375000~~chr21:42975000-43000000,
chr21:39625000-39650000~~chr21:42975000-43000000,
chr21:42050000-42075000~~chr21:42975000-43000000,
chr21:42975000-43000000~~chr21:43325000-43350000,
chr21:42975000-43000000~~chr21:43350000-43375000,
chr21:42975000-43000000~~chr21:43575000-43600000,
chr21:42975000-43000000~~chr21:43650000-43675000,
chr21:42975000-43000000~~chr21:44250000-44275000,
chr21:42975000-43000000~~chr21:44325000-44350000,
chr21:42975000-43000000~~chr21:44800000-44825000,