Browse_each

Basic information

CohesinDB ID: CDBP00420564

Locus: chr21-42991464-42993497

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE105028, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR917QNE, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE101921, GSE206145-NatGen2015, GSE138105, GSE116344, ENCSR879KXD, GSE206145, ENCSR000HPG, ENCSR153HNT, GSE68388, GSE83726, ENCSR000ECS

Cell type: RPE, H1-hESC, Fibroblast, HCT-116, Hela-Kyoto, RH4, SLK, Ishikawa, HCAEC, HeLa-S3, IMR-90, HSPC, K-562, Liver, HFFc6, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.811

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 83% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 50%, "7_Enh": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, MEIS2, XBP1, TBL1X, PATZ1, FOXA1, PBX2, LEO1, TFAP4, HDGF, ATF3, ZFP64, ZNF362, THAP1, RUNX3, ATF4, MORC2, CBFB, ZNF189, SMARCE1, PAX5, MITF, ZNF629, ELF1, TRIM28, TEAD1, ETV1, NFE2L2, LMO2, ESR1, OCA2, SAP30, HDAC8, USF2, CTCF, TCF12, JUN, EP300, E4F1, MNT, GATA6, DPF2, PAX8, SOX4, E2F6, TRIM24, SOX6, DEK, E2F4, E2F1, ZNF528, ZNF350, SMC1, TEAD4, GATAD2A, GTF2F1, RBPJ, EED, GLIS1, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, POU5F1, BRD3, ID3, CTBP1, MTA2, ZBTB17, ZBTB48, ZSCAN21, ZSCAN5A, NONO, SRF, DDX5, NBN, ARID3A, ERG, ETS1, MYC, SMARCA4, ARID1B, RAD21, FOXP2, GRHL3, NKX2-1, FOXK2, GABPA, STAT3, IKZF1, RCOR1, NFE2, NR2F6, MIER3, ARNTL, DACH1, NR3C1, ESRRA, CEBPB, ZNF93, LEF1, SRSF3, KMT2A, CREB1, EZH2, GABPB1, ZHX2, SPI1, EHF, IRF1, HDAC2, GATA2, TAF9B, FLI1, MXI1, SMARCA5, MRTFB, NCOA2, ATF1, ETV5, PTBP1, RUNX1, BCL6, MAFG, HDAC1, CEBPA, LDB1, AFF4, ZFX, SIN3A, SMAD3, ZNF770, TET2, ZNF18, PRDM10, SMARCC1, ZNF384, NOTCH1, RUNX2, GATA4, ARNT, NRF1, PBX4, ATF2, HMGB2, HMBOX1, CBFA2T3, FOXM1, PBX3, FOS, CDK8, SMARCB1, SUPT5H, CHD1, MED1, CSNK2A1, TEAD3, PML, ZXDB, CEBPD, TERF1, SMAD1, SUPT16H, ZNF3, C11orf30, NCOA1, L3MBTL2, TBX5, KLF16, ZNF22, RBM22, USF1, BCL11A, MAFK, FOXA2, REST, ZBTB7A, ZNF479, CCNT2, ATF7, ZHX1, PHIP, BCOR, FOXP1, TCF3, AFF1, GLIS2, AATF, SMC3, MLLT1, STAG1, ZNF394, NFATC3, TRP47, CBFA2T2, PPARG, ZNF316, MTA3, CREM, MEIS1, PAF1, CHD2, ZNF600, ZSCAN16, RBBP5, WT1, MAFF, ZNF574, ZBTB33, HOXB13, MPHOSPH8, KDM1A, YY1, RELA, ZNF318, JUNB, NEUROD1, SP140, TCF4, SKIL, HIF1A, GATA3, TAL1, MAX, NRIP1, GATA1, AGO2, ZNF143, ZNF333, PLAG1, CEBPG, GFI1B, NR2F2, NCOA3, NR2F1, NEUROG2, KDM5B, TP53, ZBTB6, PKNOX1, MED, ZNF334, MYOD1, BRD2, BHLHE40, AR, ZBTB40, YAP1, ZNF324, MYNN, NCOR1, RNF2, BRD4, ILF3, ZBTB26, CLOCK, JUND, MAZ, HSF1, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): UBE2G2,CFAP410,PFKL,HSF2BP,UMODL1,RRP1B,PKNOX1,DNMT3L,TRPM2,SUMO3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 28

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000177398, ENSG00000160199, ENSG00000160207, ENSG00000160208, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000184787, ENSG00000184900,

eachgene

Deatailed information for cohesin site CDBP00420564