- Basic information
- CohesinDB ID: CDBP00420571
- Locus: chr21-43007563-43008111
-
Data sourse: GSE132649, GSE67783
-
Cell type: T-47D, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
57% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"4_Tx": 50%,
"5_TxWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, PGR, MEIS2, FOXA1, PBX2, ZFHX2, TFAP4, SMARCE1, CDX2, TEAD1, ZNF217, ESR1, LMO2, CTCF, TCF12, BAF155, GATA6, DPF2, TRIM24, SOX6, E2F1, TEAD4, TFAP2C, MYCN, POU5F1, ID3, ZBTB48, STAT1, NBN, ERG2, ERG, OGG1, ETS1, MYC, SMARCA4, ARID1B, FOXP2, RAD21, GRHL3, FOXK2, STAT3, NKX3-1, IKZF1, LEF1, RCOR1, NR3C1, CREB1, FEZF1, GRHL2, HDAC2, GATA2, NCOA2, RUNX1, SMC1A, HDAC1, EZH2phosphoT487, SIN3A, ZFX, ERG3, CREBBP, RUNX2, GATA4, ARNT, PRDM9, CBFA2T3, CDK8, MED1, PIAS1, NIPBL, TFAP2A, HNF4A, CTBP2, FOXP1, PRDM6, AATF, TRP47, CBFA2T2, FOXA2, GTF2B, WT1, ESR2, FOXF1, HOXB13, KDM1A, YY1, RELA, ZNF148, SP140, HIF1A, GATA3, TAL1, MAF1, MAX, NRIP1, GATA1, ZNF143, NCOA3, NR2F2, GFI1B, NR2F1, KDM5B, PKNOX1, MYOD1, EGR2, AR, ZBTB40, EGLN2, EGR1, HSF1, NCOR1, RNF2, BRD4, ILF3, AHR
- Target gene symbol (double-evidenced CRMs): U2AF1,AGPAT3,PKNOX1,PDE9A,RRP1B,HSF2BP,SLC37A1,TRAPPC10,NDUFV3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 8
- Related genes and loops
- Related gene:
ENSG00000160190,
ENSG00000160191,
ENSG00000160194,
ENSG00000160199,
ENSG00000160201,
ENSG00000160207,
ENSG00000160208,
ENSG00000160216,
ENSG00000160218,
- Related loop:
chr21:27500000-27525000~~chr21:43000000-43025000,
chr21:41650000-41675000~~chr21:43000000-43025000,
chr21:42550000-42575000~~chr21:43000000-43025000,
chr21:42575000-42600000~~chr21:43000000-43025000,
chr21:42625000-42650000~~chr21:43000000-43025000,
chr21:42650000-42675000~~chr21:43000000-43025000,
chr21:42675000-42700000~~chr21:43000000-43025000,
chr21:42900000-42925000~~chr21:43000000-43025000,
chr21:43000000-43025000~~chr21:43100000-43125000,
chr21:43000000-43025000~~chr21:43175000-43200000,
chr21:43000000-43025000~~chr21:43200000-43225000,
chr21:43000000-43025000~~chr21:43275000-43300000,
chr21:43000000-43025000~~chr21:43300000-43325000,
chr21:43000000-43025000~~chr21:43325000-43350000,
chr21:43000000-43025000~~chr21:43350000-43375000,
chr21:43000000-43025000~~chr21:43575000-43600000,
chr21:43000000-43025000~~chr21:43600000-43625000,
chr21:43000000-43025000~~chr21:43625000-43650000,
chr21:43000000-43025000~~chr21:43650000-43675000,
chr21:43000000-43025000~~chr21:43675000-43700000,
chr21:43000000-43025000~~chr21:43900000-43925000,
chr21:43000000-43025000~~chr21:43975000-44000000,
chr21:43000000-43025000~~chr21:44025000-44050000,
chr21:43000000-43025000~~chr21:44050000-44075000,
chr21:43000000-43025000~~chr21:44075000-44100000,
chr21:6425000-6450000~~chr21:43000000-43025000,