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Basic information

CohesinDB ID: CDBP00420572

Locus: chr21-43008975-43009699

Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT

Cell type: K-562, Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 57% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 58%, "5_TxWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MAFG, SMC1A, ZSCAN5D, ZFX, GTF2B, WT1, SMAD3, ZNF134, ZBTB33, HDGF, ZNF384, MYC, ARNT, ZNF10, NFE2, DNMT3B, MED1, OCA2, C11orf30, TBX5, AR, BRD4, FOXP1, ZNF316

Target gene symbol (double-evidenced CRMs): HSF2BP,NDUFV3,SLC37A1,PKNOX1,U2AF1,TRAPPC10,AGPAT3,PDE9A,RRP1B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160191, ENSG00000160194, ENSG00000160199, ENSG00000160201, ENSG00000160207, ENSG00000160208, ENSG00000160216, ENSG00000160218,

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Deatailed information for cohesin site CDBP00420572