Browse_each

Basic information

CohesinDB ID: CDBP00420573

Locus: chr21-43011079-43011547

Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 57% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 55%, "5_TxWk": 44%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMC1A, ZNF316, CEBPA, MYCN, MAFG, ZFX, XBP1, ZBTB48, WT1, MAFF, FOXA1, ZSCAN5A, LEO1, ETV5, RELA, AHR, THAP1, SP140, GRHL3, ARNT, HIF1A, GATA3, DNMT3B, ZNF736, SNAI2, EZH2, ZNF3, ESR1, OCA2, C11orf30, TBX5, CTCF, MAFK, ARRB1, PAX3-FOXO1, AR, GATA2, FOXP1, MAZ, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): HSF2BP,U2AF1,RRP1B,TRAPPC10,NDUFV3,PDE9A,PKNOX1,AGPAT3,SLC37A1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160191, ENSG00000160194, ENSG00000160199, ENSG00000160201, ENSG00000160207, ENSG00000160208, ENSG00000160216, ENSG00000160218,

eachgene

Deatailed information for cohesin site CDBP00420573