- Basic information
- CohesinDB ID: CDBP00420577
- Locus: chr21-43020175-43023005
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Data sourse: ENCSR000BTU, GSE67783, GSE86191, GSE116868, GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR153HNT, ENCSR000EDE
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Cell type: RPE, Fibroblast, HCT-116, MB157, Ishikawa, HeLa-S3, K-562, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
57% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 53%,
"5_TxWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SMARCA2, FOXA1, HLF, LEO1, ATF3, NFIC, CHD7, CBFB, PAX5, TP63, CDX2, KLF5, TEAD1, TRIM28, ZNF121, SNAI2, ESR1, OCA2, USF2, CTCF, TCF12, JUN, EP300, GATA6, SOX5, PAX8, RFX5, TEAD4, JARID2, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, POU5F1, TOP2A, ZBTB48, ZSCAN5A, SRF, DDX5, SAP130, ERG2, ERG, PAX6, PBX1, OGG1, MYC, SMARCA4, RAD21, LHX2, GRHL3, GABPA, APC, STAT3, DNMT3B, TERF2, NR3C1, CEBPB, KMT2A, CREB1, MRTFA, GABPB1, GATA2, FLI1, MRTFB, NFIL3, RUNX1, BCL6, SOX13, ZFX, NFKBIA, TET2, ERG3, SMARCC1, NSD2, ZNF384, GATA4, FOXM1, NCAPH2, FOS, SMARCB1, TEAD3, MYB, SCRT2, ZNF3, TBX5, SREBF2, RBM22, USF1, BCL11A, REST, ARID1A, ZBTB7A, RBM25, BCOR, TCF3, AATF, SMC3, NCOR2, STAG1, TRP47, CBFA2T2, TBL1X, FOXA2, ZNF600, WT1, ZBTB33, CDK9, HOXB13, KDM1A, YY1, RELA, SP140, ZIC2, HIF1A, OTX2, TAL1, MAX, AGO2, CBX2, PLAG1, CEBPG, NCOA3, NR2F2, NR2F1, KDM5B, TP53, EGR2, BHLHE40, AR, RXR, EGLN2, HEXIM1, EGR1, TFIIIC, HSF1, ZBTB26, BRD4, SCRT1, CLOCK, MAZ, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): NDUFV3,HSF2BP,PDE9A,AGPAT3,TRAPPC10,RRP1B,SLC37A1,PKNOX1,U2AF1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 70
- Number of somatic mutations (non-coding): 35
- Related genes and loops
- Related gene:
ENSG00000160190,
ENSG00000160191,
ENSG00000160194,
ENSG00000160199,
ENSG00000160201,
ENSG00000160207,
ENSG00000160208,
ENSG00000160216,
ENSG00000160218,
- Related loop:
chr21:27500000-27525000~~chr21:43000000-43025000,
chr21:41650000-41675000~~chr21:43000000-43025000,
chr21:42550000-42575000~~chr21:43000000-43025000,
chr21:42575000-42600000~~chr21:43000000-43025000,
chr21:42600000-42625000~~chr21:43025000-43050000,
chr21:42625000-42650000~~chr21:43000000-43025000,
chr21:42650000-42675000~~chr21:43000000-43025000,
chr21:42675000-42700000~~chr21:43000000-43025000,
chr21:42675000-42700000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43000000-43025000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42925000-42950000~~chr21:43025000-43050000,
chr21:43000000-43025000~~chr21:43100000-43125000,
chr21:43000000-43025000~~chr21:43175000-43200000,
chr21:43000000-43025000~~chr21:43200000-43225000,
chr21:43000000-43025000~~chr21:43275000-43300000,
chr21:43000000-43025000~~chr21:43300000-43325000,
chr21:43000000-43025000~~chr21:43325000-43350000,
chr21:43000000-43025000~~chr21:43350000-43375000,
chr21:43000000-43025000~~chr21:43575000-43600000,
chr21:43000000-43025000~~chr21:43600000-43625000,
chr21:43000000-43025000~~chr21:43625000-43650000,
chr21:43000000-43025000~~chr21:43650000-43675000,
chr21:43000000-43025000~~chr21:43675000-43700000,
chr21:43000000-43025000~~chr21:43900000-43925000,
chr21:43000000-43025000~~chr21:43975000-44000000,
chr21:43000000-43025000~~chr21:44025000-44050000,
chr21:43000000-43025000~~chr21:44050000-44075000,
chr21:43000000-43025000~~chr21:44075000-44100000,
chr21:43025000-43050000~~chr21:43175000-43200000,
chr21:43025000-43050000~~chr21:43300000-43325000,
chr21:43025000-43050000~~chr21:43350000-43375000,
chr21:43025000-43050000~~chr21:43650000-43675000,
chr21:43025000-43050000~~chr21:43725000-43750000,
chr21:43025000-43050000~~chr21:44075000-44100000,
chr21:43025000-43050000~~chr21:44500000-44525000,
chr21:6425000-6450000~~chr21:43000000-43025000,
chr21:6425000-6450000~~chr21:43025000-43050000,