Browse_each

Basic information

CohesinDB ID: CDBP00420578

Locus: chr21-43023655-43024103

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 57% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 62%, "5_TxWk": 34%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, SMARCA2, FOXA1, HLF, LEO1, ATF3, NFIC, CHD7, CBFB, PAX5, TP63, CDX2, KLF5, TEAD1, TRIM28, ZNF121, SNAI2, ESR1, OCA2, USF2, CTCF, TCF12, JUN, EP300, GATA6, SOX5, PAX8, RFX5, TEAD4, JARID2, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, POU5F1, TOP2A, ZBTB48, ZSCAN5A, SRF, DDX5, SAP130, ERG2, ERG, PAX6, PBX1, OGG1, MYC, SMARCA4, RAD21, LHX2, GRHL3, GABPA, APC, STAT3, DNMT3B, TERF2, NR3C1, CEBPB, KMT2A, CREB1, MRTFA, GABPB1, GATA2, FLI1, MRTFB, NFIL3, RUNX1, BCL6, SOX13, ZFX, NFKBIA, TET2, ERG3, SMARCC1, NSD2, ZNF384, GATA4, FOXM1, NCAPH2, FOS, SMARCB1, TEAD3, MYB, SCRT2, ZNF3, TBX5, SREBF2, RBM22, USF1, BCL11A, REST, ARID1A, ZBTB7A, RBM25, BCOR, TCF3, AATF, SMC3, NCOR2, STAG1, TRP47, CBFA2T2, TBL1X, FOXA2, ZNF600, WT1, ZBTB33, CDK9, HOXB13, KDM1A, YY1, RELA, SP140, ZIC2, HIF1A, OTX2, TAL1, MAX, AGO2, CBX2, PLAG1, CEBPG, NCOA3, NR2F2, NR2F1, KDM5B, TP53, EGR2, BHLHE40, AR, RXR, EGLN2, HEXIM1, EGR1, TFIIIC, HSF1, ZBTB26, BRD4, SCRT1, CLOCK, MAZ, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): SLC37A1,U2AF1,RRP1B,HSF2BP,AGPAT3,PKNOX1,TRAPPC10,PDE9A,NDUFV3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 8

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160191, ENSG00000160194, ENSG00000160199, ENSG00000160201, ENSG00000160207, ENSG00000160208, ENSG00000160216, ENSG00000160218,

eachgene

Deatailed information for cohesin site CDBP00420578