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Basic information

CohesinDB ID: CDBP00420581

Locus: chr21-43028717-43029018

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 57% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 72%, "5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: BRD1, ZNF263, MYCN, SIRT6, ZFX, ZBTB48, WT1, ZSCAN5A, ERG3, CDK9, NSD2, RELA, ZNF384, AHR, MYC, SP140, ARNT, NKX2-1, TAL1, MITF, DNMT3B, ARNTL, ELF1, NR2F1, ZNF3, TP53, ZNF334, NFKB1, CTCF, AR, ARID1A, MXD3, BRD4, MAZ, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): PDXK,PDE9A,NDUFV3,HSF2BP,TSPEAR,PKNOX1,RRP1B,TRAPPC10

Function elements

Human SNPs: .

Number of somatic mutations (coding): 48

Number of somatic mutations (non-coding): 18

Related genes and loops

Related gene: ENSG00000160191, ENSG00000160194, ENSG00000160199, ENSG00000160207, ENSG00000160208, ENSG00000160209, ENSG00000160218, ENSG00000175894,

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Deatailed information for cohesin site CDBP00420581