- Basic information
- CohesinDB ID: CDBP00420583
- Locus: chr21-43031865-43032624
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, ENCSR153HNT
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Cell type: K-562, Fibroblast, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
57% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"4_Tx": 54%,
"5_TxWk": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: OGG1, ZFX, ZBTB48, BRD4, WT1, APC, CTCF, LEO1
- Target gene symbol (double-evidenced CRMs): RRP1B,PKNOX1,TSPEAR,NDUFV3,TRAPPC10,PDE9A,PDXK,HSF2BP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 18
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000160191,
ENSG00000160194,
ENSG00000160199,
ENSG00000160207,
ENSG00000160208,
ENSG00000160209,
ENSG00000160218,
ENSG00000175894,
- Related loop:
chr21:42600000-42625000~~chr21:43025000-43050000,
chr21:42675000-42700000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42925000-42950000~~chr21:43025000-43050000,
chr21:43025000-43050000~~chr21:43175000-43200000,
chr21:43025000-43050000~~chr21:43300000-43325000,
chr21:43025000-43050000~~chr21:43350000-43375000,
chr21:43025000-43050000~~chr21:43650000-43675000,
chr21:43025000-43050000~~chr21:43725000-43750000,
chr21:43025000-43050000~~chr21:44075000-44100000,
chr21:43025000-43050000~~chr21:44500000-44525000,
chr21:6425000-6450000~~chr21:43025000-43050000,