- Basic information
- CohesinDB ID: CDBP00420586
- Locus: chr21-43036478-43039973
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Data sourse: ENCSR230ZWH, GSE67783, GSE86191, GSE98367, GSE111913, GSE206145-NatGen2015, ENCSR153HNT, GSE126755, ENCSR917QNE
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Cell type: Fibroblast, HCT-116, RT-112, K-562, Liver, Neutrophil, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SMC3,SA1,Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
57% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"4_Tx": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): TRAPPC10,TSPEAR,PDE9A,NDUFV3,RRP1B,PKNOX1,HSF2BP,PDXK
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 18
- Related genes and loops
- Related gene:
ENSG00000160191,
ENSG00000160194,
ENSG00000160199,
ENSG00000160207,
ENSG00000160208,
ENSG00000160209,
ENSG00000160218,
ENSG00000175894,
- Related loop:
chr21:42600000-42625000~~chr21:43025000-43050000,
chr21:42675000-42700000~~chr21:43025000-43050000,
chr21:42900000-42925000~~chr21:43025000-43050000,
chr21:42925000-42950000~~chr21:43025000-43050000,
chr21:43025000-43050000~~chr21:43175000-43200000,
chr21:43025000-43050000~~chr21:43300000-43325000,
chr21:43025000-43050000~~chr21:43350000-43375000,
chr21:43025000-43050000~~chr21:43650000-43675000,
chr21:43025000-43050000~~chr21:43725000-43750000,
chr21:43025000-43050000~~chr21:44075000-44100000,
chr21:43025000-43050000~~chr21:44500000-44525000,
chr21:6425000-6450000~~chr21:43025000-43050000,