- Basic information
- CohesinDB ID: CDBP00420604
- Locus: chr21-43074203-43077637
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE126634, GSE116868, ENCSR404BPV, GSE105028, GSE131606, GSE108869, GSE25021, GSE165895, ENCSR000EFJ, ENCSR000BTU, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE206145-NatGen2015, ENCSR198ZYJ, GSE130135, GSE116344, GSE106870, ENCSR338DUC, GSE98367, GSE206145, GSE62063, GSE131956, GSE111913, ENCSR335RKQ, ENCSR000EDE, ENCSR153HNT, GSE126755, ENCSR000ECS
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Cell type: RH4, CVI-hiPSC, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, IMR-90, K-562, HFFc6, DKO, H1-hESC, MB157, GBM39, RT-112, HAP1, Macrophage, Ramos, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, Neutrophil, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 11% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.700
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
57% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"13_ReprPC": 16%,
"11_BivFlnk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): CBS
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 50
- Number of somatic mutations (non-coding): 18
- Related genes and loops