- Basic information
- CohesinDB ID: CDBP00420643
- Locus: chr21-43203180-43204296
-
Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
-
Cell type: K-562, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
57% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 48%,
"14_ReprPCWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CHD8, FOXA2, MYCN, POU5F1, ZNF263, TOP2A, ZFX, XBP1, WT1, ZBTB48, FOXA1, ZNF134, ERG3, ETV5, RELA, IRF2, AHR, MYC, CTCFL, SP140, GRHL3, ARNT, PRDM9, TAL1, MED1, TERF1, TRIM28, EZH2, OCA2, ZNF334, CTCF, BCL11A, GSPT2, BRD4, ZNF766, MAZ, SMC3, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): WDR4,PDXK,TFF2,PDE9A,TFF1,CSTB,TRAPPC10,TMPRSS2,DNMT3L,TRPM2,MX2,TMPRSS3,PKNOX1,NDUFV3,HSF2BP,RRP1B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000183486,
ENSG00000184012,
ENSG00000160181,
ENSG00000160182,
ENSG00000160183,
ENSG00000160191,
ENSG00000160193,
ENSG00000160194,
ENSG00000160199,
ENSG00000160207,
ENSG00000160208,
ENSG00000160209,
ENSG00000160213,
ENSG00000160218,
ENSG00000142182,
ENSG00000142185,
- Related loop:
chr21:41375000-41400000~~chr21:43200000-43225000,
chr21:41525000-41550000~~chr21:43200000-43225000,
chr21:42150000-42175000~~chr21:43200000-43225000,
chr21:42275000-42300000~~chr21:43175000-43200000,
chr21:42350000-42375000~~chr21:43175000-43200000,
chr21:42350000-42375000~~chr21:43200000-43225000,
chr21:42550000-42575000~~chr21:43175000-43200000,
chr21:42575000-42600000~~chr21:43175000-43200000,
chr21:42600000-42625000~~chr21:43175000-43200000,
chr21:42625000-42650000~~chr21:43175000-43200000,
chr21:42650000-42675000~~chr21:43175000-43200000,
chr21:42675000-42700000~~chr21:43200000-43225000,
chr21:42725000-42750000~~chr21:43175000-43200000,
chr21:42725000-42750000~~chr21:43200000-43225000,
chr21:42750000-42775000~~chr21:43175000-43200000,
chr21:42775000-42800000~~chr21:43175000-43200000,
chr21:42775000-42800000~~chr21:43200000-43225000,
chr21:42800000-42825000~~chr21:43175000-43200000,
chr21:42850000-42875000~~chr21:43175000-43200000,
chr21:42850000-42875000~~chr21:43200000-43225000,
chr21:42875000-42900000~~chr21:43175000-43200000,
chr21:42900000-42925000~~chr21:43175000-43200000,
chr21:42900000-42925000~~chr21:43200000-43225000,
chr21:42925000-42950000~~chr21:43175000-43200000,
chr21:42950000-42975000~~chr21:43175000-43200000,
chr21:42950000-42975000~~chr21:43200000-43225000,
chr21:43000000-43025000~~chr21:43175000-43200000,
chr21:43000000-43025000~~chr21:43200000-43225000,
chr21:43025000-43050000~~chr21:43175000-43200000,
chr21:43175000-43200000~~chr21:43275000-43300000,
chr21:43175000-43200000~~chr21:43300000-43325000,
chr21:43175000-43200000~~chr21:43325000-43350000,
chr21:43175000-43200000~~chr21:43350000-43375000,
chr21:43175000-43200000~~chr21:43575000-43600000,
chr21:43175000-43200000~~chr21:43600000-43625000,
chr21:43175000-43200000~~chr21:43625000-43650000,
chr21:43175000-43200000~~chr21:43650000-43675000,
chr21:43175000-43200000~~chr21:43725000-43750000,
chr21:43175000-43200000~~chr21:43750000-43775000,
chr21:43175000-43200000~~chr21:43850000-43875000,
chr21:43175000-43200000~~chr21:43875000-43900000,
chr21:43175000-43200000~~chr21:43950000-43975000,
chr21:43175000-43200000~~chr21:43975000-44000000,
chr21:43175000-43200000~~chr21:44025000-44050000,
chr21:43175000-43200000~~chr21:44050000-44075000,
chr21:43175000-43200000~~chr21:44075000-44100000,
chr21:43175000-43200000~~chr21:44275000-44300000,
chr21:43175000-43200000~~chr21:44375000-44400000,
chr21:43200000-43225000~~chr21:43300000-43325000,
chr21:43200000-43225000~~chr21:43325000-43350000,
chr21:43200000-43225000~~chr21:43350000-43375000,
chr21:43200000-43225000~~chr21:43575000-43600000,
chr21:43200000-43225000~~chr21:43600000-43625000,
chr21:43200000-43225000~~chr21:43625000-43650000,
chr21:43200000-43225000~~chr21:43650000-43675000,
chr21:43200000-43225000~~chr21:43750000-43775000,
chr21:43200000-43225000~~chr21:44025000-44050000,
chr21:43200000-43225000~~chr21:44250000-44275000,
chr21:43200000-43225000~~chr21:44350000-44375000,
chr21:6025000-6050000~~chr21:43200000-43225000,
chr21:6075000-6100000~~chr21:43175000-43200000,
chr21:6100000-6125000~~chr21:43175000-43200000,
chr21:6100000-6125000~~chr21:43200000-43225000,
chr21:6125000-6150000~~chr21:43175000-43200000,
chr21:6125000-6150000~~chr21:43200000-43225000,
chr21:6550000-6575000~~chr21:43175000-43200000,