- Basic information
- CohesinDB ID: CDBP00420648
- Locus: chr21-43262337-43262934
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE67783, GSE72082, GSE86191, GSE98367, GSE110061, ENCSR000EGW, GSE76893, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, GSE120943, ENCSR153HNT, ENCSR635OSG, ENCSR703TNG, GSE25021, GSE50893, ENCSR000ECS
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Cell type: MCF-7, Macrophage, RPE, Fibroblast, HCT-116, Monocytes, GM18505, Hep-G2, HeLa-S3, HSPC, K-562, Liver, GM18951, GM19099
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 89%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, ZNF195, ZNF621, XBP1, FOXA1, SUZ12, ZFHX2, ZBTB7B, ATF3, ZNF112, THAP1, ZBTB5, PRDM1, ZNF444, ZNF429, ZNF467, ZNF121, BCLAF1, TRIM28, LMO2, ESR1, OCA2, ZNF571, ZIK1, CTCF, TCF12, ZNF695, GLI4, DEK, ZNF512B, ZNF776, ZNF528, ZNF175, EHMT2, TFAP2C, YBX1, POU2F2, CHD8, NANOG, POU5F1, ZNF239, MYCN, ZNF263, TOP2A, ZNF317, ZBTB48, STAT1, ZNF488, DDX5, HIC1, ERG2, ZNF300, ERG, ETS1, RFX1, RAD21, GRHL3, BATF3, GABPA, XRCC5, ZNF398, ZNF639, ESRRA, HNRNPL, CREB1, ZNF560, EZH2, GRHL2, ZNF292, HES1, SSRP1, GATAD2B, ZNF146, ZNF785, NCOA2, SALL2, CC2D1A, AHRR, HDAC1, ZNF707, CRY1, ZFX, ZFP37, ZNF473, ERG3, CREBBP, ZNF184, ZNF280C, NFIB, SOX11, PRDM9, SMARCB1, CHD1, ZNF680, ZNF3, NCOA1, USF1, NIPBL, SP1, BCL11A, REST, ZBTB7A, HNRNPLL, SALL1, TCF3, SMC3, STAG1, ZNF394, ZNF207, MTA3, CHD2, WT1, ZNF662, ZKSCAN1, YY1, RELA, TARDBP, ZNF148, ZNF266, ZNF521, MCM3, ZNF311, MAF1, MAX, NRIP1, ZNF143, ZSCAN26, NCOA3, ZNF544, ZNF791, TCF7L2, PKNOX1, BCL6B, ZSCAN22, EGR2, ARRB1, BHLHE40, AR, ZBTB40, ZBTB26, HSF1, RNF2, ZNF248, PRDM2, BRD4, CLOCK, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): RSPH1,SLC37A1,HSF2BP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops