- Basic information
- CohesinDB ID: CDBP00420655
- Locus: chr21-43294387-43294818
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Data sourse: ENCSR054FKH, ENCSR153HNT, GSE72082, ENCSR167MTG
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Cell type: K-562, Hep-G2
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 62%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, HMG20A, FOXA1, SUZ12, RXRB, THRB, NFIC, ZFP64, MXD4, MITF, ZNF320, TEAD1, KLF6, LMO2, RCOR2, ESR1, USF2, CTCF, JUN, EP300, SOX5, FOXA3, GATAD2A, RBPJ, MLX, MYCN, ZBTB17, ZBTB48, GATAD1, SAP130, HNF4G, PBX1, MYC, HOMEZ, RXRA, XRCC5, ZNF614, IKZF1, MIER3, NR2F6, NR3C1, CEBPB, ESRRA, KMT2A, ZNF565, EBF3, SPI1, MIXL1, TFE3, ZNF257, ZNF644, ZGPAT, NFIL3, ZNF554, RUNX1, THAP11, BCL6, CEBPA, SOX13, ZFX, SP5, RARA, PRPF4, CREBBP, ARNT, ATF2, SMAD4, CBFA2T3, TEAD3, ZNF3, KLF9, L3MBTL2, TBX5, SETDB1, USF1, SP1, HNF4A, ZNF479, BCOR, FOXP1, TCF3, NCOR2, STAG1, ZNF816, CBFA2T2, MEF2B, PPARG, FOXA2, CBX3, EBF1, MIER2, KDM1A, YY1, RELA, SP140, TAL1, MAX, PLAG1, CEBPG, NR2F2, ELF3, KAT8, ARID4B, NFKBIZ, BHLHE40, AR, ZNF280D, RNF2, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): HSF2BP,PKNOX1,DNMT3L,WDR4,PFKL,ABCG1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160179,
ENSG00000160193,
ENSG00000160199,
ENSG00000160207,
ENSG00000142182,
ENSG00000141959,
- Related loop:
chr21:28775000-28800000~~chr21:43275000-43300000,
chr21:42300000-42325000~~chr21:43275000-43300000,
chr21:42850000-42875000~~chr21:43275000-43300000,
chr21:42950000-42975000~~chr21:43275000-43300000,
chr21:43000000-43025000~~chr21:43275000-43300000,
chr21:43175000-43200000~~chr21:43275000-43300000,
chr21:43275000-43300000~~chr21:43600000-43625000,
chr21:43275000-43300000~~chr21:43625000-43650000,
chr21:43275000-43300000~~chr21:44250000-44275000,
chr21:43275000-43300000~~chr21:44275000-44300000,
chr21:6025000-6050000~~chr21:43275000-43300000,
chr21:6550000-6575000~~chr21:43275000-43300000,