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Basic information

CohesinDB ID: CDBP00420656

Locus: chr21-43295496-43295735

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 65% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 39%, "9_Het": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, HMG20A, FOXA1, SUZ12, RXRB, THRB, NFIC, ZFP64, MXD4, MITF, ZNF320, TEAD1, KLF6, LMO2, RCOR2, ESR1, USF2, CTCF, JUN, EP300, SOX5, FOXA3, GATAD2A, RBPJ, MLX, MYCN, ZBTB17, ZBTB48, GATAD1, SAP130, HNF4G, PBX1, MYC, HOMEZ, RXRA, XRCC5, ZNF614, IKZF1, MIER3, NR2F6, NR3C1, CEBPB, ESRRA, KMT2A, ZNF565, EBF3, SPI1, MIXL1, TFE3, ZNF257, ZNF644, ZGPAT, NFIL3, ZNF554, RUNX1, THAP11, BCL6, CEBPA, SOX13, ZFX, SP5, RARA, PRPF4, CREBBP, ARNT, ATF2, SMAD4, CBFA2T3, TEAD3, ZNF3, KLF9, L3MBTL2, TBX5, SETDB1, USF1, SP1, HNF4A, ZNF479, BCOR, FOXP1, TCF3, NCOR2, STAG1, ZNF816, CBFA2T2, MEF2B, PPARG, FOXA2, CBX3, EBF1, MIER2, KDM1A, YY1, RELA, SP140, TAL1, MAX, PLAG1, CEBPG, NR2F2, ELF3, KAT8, ARID4B, NFKBIZ, BHLHE40, AR, ZNF280D, RNF2, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): HSF2BP,PKNOX1,DNMT3L,WDR4,ABCG1,PFKL

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000160179, ENSG00000160193, ENSG00000160199, ENSG00000160207, ENSG00000142182, ENSG00000141959,

eachgene

Deatailed information for cohesin site CDBP00420656