- Basic information
- CohesinDB ID: CDBP00420675
- Locus: chr21-43409116-43421927
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Data sourse: ENCSR000BLD, GSE104888, ENCSR230ZWH, GSE72082, ENCSR000BSB, ENCSR501LQA, GSE116868, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE121355, GSE131606, ENCSR330ELC, GSE108869, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE165895, GSE67783, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR806UKK, GSE120943, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE138105, ENCSR895JMI, ENCSR338DUC, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR981FDC, GSE62063, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE110061, GSE129526, ENCSR000HPG, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, ENCSR153HNT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR000ECS, GSE38411
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Cell type: RH4, GM2610, SLK, Liver, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, HEKn, Ishikawa, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, HFFc6, DKO, H1-hESC, Monocytes, MB157, GM12878, GM2588, SK-N-SH, RT-112, HeLa-Tet-On, Macrophage, Ramos, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, A-549, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 28% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.611
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TES,Intragenic,Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
65% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 24%,
"7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: .
- Target gene symbol (double-evidenced CRMs): SIK1
- Function elements
- Human SNPs: Systolic_blood_pressure
- Number of somatic mutations (coding): 522
- Number of somatic mutations (non-coding): 549
- Related genes and loops