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Basic information

CohesinDB ID: CDBP00420735

Locus: chr21-43618660-43619178

Data sourse: GSE116344, GSE111913, GSE67783, GSE86191

Cell type: RT-112, RH4, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 70% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 75%, "5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, CHD8, SMC1A, FOXA2, CBX3, POU5F1, CRY1, ZFX, STAG2, XBP1, WT1, SMAD3, STAT1, FOXA1, SRF, CDK9, HOXB13, ERG, HOXC5, YY1, CREBBP, ZBTB2, AHR, RUNX2, EZH1, GATA4, ZNF280A, RAD21, PBX4, DAXX, TCF4, ARNT, SKIL, HIF1A, SMC3, GATA3, ZEB2, STAT3, TAL1, NRIP1, ZNF143, CDK8, IKZF1, MED1, CDX2, ZNF467, CEBPB, NCOA3, TEAD3, TRIM28, SCRT2, NR2F1, PIAS1, KDM5B, ESR1, KLF8, SETDB1, ZSCAN22, CTCF, TCF12, JUN, BAF155, NIPBL, EP300, HNF4A, AR, GATA6, SP1, SPI1, MIXL1, GATA2, REST, EGLN2, TRIM24, ZNF280D, BRD4, MAZ, ZNF528, SMC1, NCOA2, FOXA3, NCOR2, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): HSF2BP,NDUFV3,SLC37A1,PKNOX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160194, ENSG00000160199, ENSG00000160207,

eachgene

Deatailed information for cohesin site CDBP00420735