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Basic information

CohesinDB ID: CDBP00420740

Locus: chr21-43627385-43627862

Data sourse: ENCSR000BTQ, ENCSR703TNG, GSE206145-GSE177045, GSE72082

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 70% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 71%, "14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, ZNF316, FOXA2, SIN3A, DUX4, FOXA1, FOXF1, HOXB13, TFAP4, ERG, CREBBP, AHR, MYC, RAD21, ARNT, GATA3, FOXM1, NKX3-1, CDX2, TLE3, NR3C1, CEBPB, TEAD1, ZNF573, PIAS1, ZNF217, ESR1, GRHL2, TCF12, BAF155, TFAP2A, AR, HDAC2, GATA2, BRD4, CTBP2, FOXP1, TFAP2C

Target gene symbol (double-evidenced CRMs): HSF2BP,PKNOX1,WDR4,SIK1,NDUFV3,SLC37A1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160193, ENSG00000160194, ENSG00000160199, ENSG00000142178, ENSG00000160207,

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Deatailed information for cohesin site CDBP00420740