- Basic information
- CohesinDB ID: CDBP00420742
- Locus: chr21-43634076-43634294
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Data sourse: GSE116344, ENCSR153HNT
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Cell type: K-562, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
70% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, SMARCA2, ZNF496, HMG20A, E2F7, SOX2, NME2, XBP1, FOXA1, HLF, SUZ12, RXRB, ZFHX2, KDM3A, HDGF, ATF3, NFIC, ZNF362, CHD7, PRDM1, ZNF444, ZNF532, ATF4, PAX5, TP63, ZSCAN4, MITF, SFPQ, JMJD1C, TEAD1, ELF1, KLF6, SNAI2, SMAD5, ESR1, OCA2, LMO2, RCOR2, MLL, USF2, CTCF, JUN, TCF12, EP300, NUTM1, BAF155, MNT, SOX5, GATA6, DPF2, PAX8, TRIM24, RFX5, ZNF512B, SMC1, TEAD4, FOXA3, GATAD2A, PDX1, TFAP2C, EED, GLIS1, POU2F2, CHD8, POU5F1, MYCN, TOP2A, ZNF263, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZNF205, DDX5, SAP130, ERG2, ARID3A, TBP, ZNF300, ERG, CHD4, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, ZNF614, NKX3-1, IKZF1, RCOR1, HNRNPH1, MIER3, ARNTL, NR3C1, ESRRA, SRSF3, CEBPB, HNRNPL, ZNF750, CREB1, EZH2, TBL1XR1, GRHL2, GABPB1, ZHX2, SPI1, MIXL1, EHF, HDAC2, SSRP1, GATA2, ZNF644, GATAD2B, MXD3, SIX2, FLI1, ZGPAT, MRTFB, NFIL3, RUNX1, THAP11, BCL6, SMC1A, CEBPA, SIN3A, ZFX, AFF4, SOX13, SMAD3, TET2, ERG3, CBX8, ZNF770, ZNF513, SMARCC1, PRDM10, CREBBP, ZNF384, RARA, TAF15, RUNX2, GATA4, ZNF184, PBX4, ARNT, NFIB, SOX11, PRDM9, SMAD4, FOS, CDK8, MED1, ZEB1, TEAD3, KDM6B, CEBPD, ZNF680, PIAS1, NR1H2, NCOA1, USF1, BCL11A, SP1, NIPBL, HNF4A, NKX2-5, REST, RBM25, POU2F3, ZHX1, ATF7, HNRNPLL, FOXP1, SMC3, ELL2, STAG2, STAG1, TRP47, ZNF316, AGO1, FOXA2, TBL1X, ZNF207, MTA3, PPARG, ZSCAN16, GTF2B, ZNF692, WT1, ESR2, ZNF662, ZBTB33, CDK9, HOXB13, KDM1A, ZNF19, RELA, YY1, TARDBP, JUNB, SP140, HIF1A, ZNF311, GATA3, MAX, ZNF143, GATA1, CBX2, CEBPG, KLF4, NCOA3, NR2F2, ZNF512, NEUROG2, TCF7L2, KDM5B, TP53, PKNOX1, NFKB1, EGR2, PHOX2B, ELF3, KAT8, BHLHE40, AR, RXR, ZNF324, EGLN2, EGR1, HSF1, RNF2, NCOR1, BRD4, JUND, SCRT1, CLOCK, CUX1, MAZ, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): NDUFV3,SIK1,WDR4,SLC37A1,PKNOX1,HSF2BP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160190,
ENSG00000160193,
ENSG00000160194,
ENSG00000160199,
ENSG00000142178,
ENSG00000160207,
- Related loop:
chr21:42150000-42175000~~chr21:43625000-43650000,
chr21:42575000-42600000~~chr21:43625000-43650000,
chr21:42600000-42625000~~chr21:43625000-43650000,
chr21:42800000-42825000~~chr21:43625000-43650000,
chr21:42875000-42900000~~chr21:43625000-43650000,
chr21:42900000-42925000~~chr21:43625000-43650000,
chr21:42925000-42950000~~chr21:43625000-43650000,
chr21:43000000-43025000~~chr21:43625000-43650000,
chr21:43175000-43200000~~chr21:43625000-43650000,
chr21:43200000-43225000~~chr21:43625000-43650000,
chr21:43275000-43300000~~chr21:43625000-43650000,
chr21:43300000-43325000~~chr21:43625000-43650000,
chr21:43325000-43350000~~chr21:43625000-43650000,
chr21:43350000-43375000~~chr21:43625000-43650000,
chr21:43425000-43450000~~chr21:43625000-43650000,
chr21:43475000-43500000~~chr21:43625000-43650000,
chr21:6075000-6100000~~chr21:43625000-43650000,
chr21:6100000-6125000~~chr21:43625000-43650000,
chr21:6125000-6150000~~chr21:43625000-43650000,
chr21:6425000-6450000~~chr21:43625000-43650000,
chr21:6500000-6525000~~chr21:43625000-43650000,
chr21:6550000-6575000~~chr21:43625000-43650000,