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Basic information

CohesinDB ID: CDBP00420743

Locus: chr21-43634658-43635007

Data sourse: GSE68388, GSE138105

Cell type: SLK, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 70% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 80%, "5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, SMARCA2, ZNF496, HMG20A, E2F7, SOX2, NME2, XBP1, FOXA1, HLF, SUZ12, RXRB, ZFHX2, KDM3A, HDGF, ATF3, NFIC, ZNF362, CHD7, PRDM1, ZNF444, ZNF532, ATF4, PAX5, TP63, ZSCAN4, MITF, SFPQ, JMJD1C, TEAD1, ELF1, KLF6, SNAI2, SMAD5, ESR1, OCA2, LMO2, RCOR2, MLL, USF2, CTCF, JUN, TCF12, EP300, NUTM1, BAF155, MNT, SOX5, GATA6, DPF2, PAX8, TRIM24, RFX5, ZNF512B, SMC1, TEAD4, FOXA3, GATAD2A, PDX1, TFAP2C, EED, GLIS1, POU2F2, CHD8, POU5F1, MYCN, TOP2A, ZNF263, CTBP1, ZSCAN21, ZBTB17, ZBTB48, ZNF205, DDX5, SAP130, ERG2, ARID3A, TBP, ZNF300, ERG, CHD4, MYC, SMARCA4, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, ZNF614, NKX3-1, IKZF1, RCOR1, HNRNPH1, MIER3, ARNTL, NR3C1, ESRRA, SRSF3, CEBPB, HNRNPL, ZNF750, CREB1, EZH2, TBL1XR1, GRHL2, GABPB1, ZHX2, SPI1, MIXL1, EHF, HDAC2, SSRP1, GATA2, ZNF644, GATAD2B, MXD3, SIX2, FLI1, ZGPAT, MRTFB, NFIL3, RUNX1, THAP11, BCL6, SMC1A, CEBPA, SIN3A, ZFX, AFF4, SOX13, SMAD3, TET2, ERG3, CBX8, ZNF770, ZNF513, SMARCC1, PRDM10, CREBBP, ZNF384, RARA, TAF15, RUNX2, GATA4, ZNF184, PBX4, ARNT, NFIB, SOX11, PRDM9, SMAD4, FOS, CDK8, MED1, ZEB1, TEAD3, KDM6B, CEBPD, ZNF680, PIAS1, NR1H2, NCOA1, USF1, BCL11A, SP1, NIPBL, HNF4A, NKX2-5, REST, RBM25, POU2F3, ZHX1, ATF7, HNRNPLL, FOXP1, SMC3, ELL2, STAG2, STAG1, TRP47, ZNF316, AGO1, FOXA2, TBL1X, ZNF207, MTA3, PPARG, ZSCAN16, GTF2B, ZNF692, WT1, ESR2, ZNF662, ZBTB33, CDK9, HOXB13, KDM1A, ZNF19, RELA, YY1, TARDBP, JUNB, SP140, HIF1A, ZNF311, GATA3, MAX, ZNF143, GATA1, CBX2, CEBPG, KLF4, NCOA3, NR2F2, ZNF512, NEUROG2, TCF7L2, KDM5B, TP53, PKNOX1, NFKB1, EGR2, PHOX2B, ELF3, KAT8, BHLHE40, AR, RXR, ZNF324, EGLN2, EGR1, HSF1, RNF2, NCOR1, BRD4, JUND, SCRT1, CLOCK, CUX1, MAZ, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): PKNOX1,HSF2BP,SIK1,NDUFV3,WDR4,SLC37A1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 1

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160190, ENSG00000160193, ENSG00000160194, ENSG00000160199, ENSG00000142178, ENSG00000160207,

eachgene

Deatailed information for cohesin site CDBP00420743