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Basic information

CohesinDB ID: CDBP00420758

Locus: chr21-43669130-43669692

Data sourse: GSE67783, GSE111913, ENCSR153HNT

Cell type: K-562, RT-112, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 70% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 69%, "4_Tx": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRP47, NANOG, CHD8, POU2F2, ZNF316, POU5F1, ZNF263, TOP2A, NFATC1, ZFX, MYCN, XBP1, SIRT6, ZBTB48, WT1, ZMYND11, PAF1, FOXA1, ERG3, ZBTB33, RBFOX2, LEO1, BCL3, ERG, YY1, RELA, KDM1A, OGG1, NEUROD1, ATF3, MYC, CDK6, THAP1, SP140, GRHL3, ARNT, SOX11, CTNNB1, CBFB, ZNF48, GLYR1, STAT3, XRCC5, PBX3, APC, SUPT5H, AGO2, ZNF143, HNRNPH1, DNMT3B, NCOA3, TEAD3, SNAI2, EZH2, KDM5B, OCA2, CTCF, RBM22, ZHX2, SPI1, AR, GATA2, MXD3, ZBTB26, BRD4, TCF3, CLOCK, E2F1, MAZ, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): PDXK,PFKL,PKNOX1,CSTB,TRPM2,UBE2G2,CBS,UMODL1,RRP1B,NDUFV3,CFAP410,WDR4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000177398, ENSG00000160193, ENSG00000160194, ENSG00000160199, ENSG00000160200, ENSG00000160208, ENSG00000160209, ENSG00000160213, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000184787,

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Deatailed information for cohesin site CDBP00420758