Browse_each

Basic information

CohesinDB ID: CDBP00420763

Locus: chr21-43675087-43675363

Data sourse: ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 70% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 79%, "5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, NANOG, SMC1A, CHD8, TBL1X, POU5F1, CBFA2T2, MYCN, SOX2, ZFX, ZNF600, POU4F2, XBP1, ZBTB48, WT1, FOXA1, TET2, ERG3, DDX5, ERG, YY1, RELA, ZNF384, NEUROD1, ZNF362, RAD21, CHD7, ARNT, SP140, GRHL3, GLYR1, MECOM, TAL1, SUPT5H, ZNF143, AGO2, ZNF736, TEAD1, ZNF680, EZH2, ESR1, TP53, OCA2, GRHL2, ZNF334, SREBF2, ZNF22, CTCF, RBM22, EP300, AR, ZBTB40, SCRT1, BRD4, FOXP1, RELB, HCFC1R1, MAZ, SMC3, POU2F2

Target gene symbol (double-evidenced CRMs): WDR4,DNMT3L,PKNOX1,RRP1B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 10

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160193, ENSG00000160199, ENSG00000160208, ENSG00000142182,

eachgene

Deatailed information for cohesin site CDBP00420763