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Basic information

CohesinDB ID: CDBP00420764

Locus: chr21-43676274-43676773

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 70% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 87%, "5_TxWk": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, SMC1A, PPARG, TBL1X, BRD1, POU5F1, RUNX1T1, MYCN, ZFX, KDM4C, XBP1, PAF1, WT1, ZBTB48, ZSCAN5A, GTF2B, TET2, LEO1, HOXB13, NSD2, ERG, YY1, RELA, CREBBP, ATF3, MYC, CDK6, SP140, GRHL3, CBFB, GLYR1, ZNF10, ZNF143, AGO2, CDK8, DNMT3B, SMARCB1, SUPT5H, TERF2, FOS, NR3C1, NCOA3, TEAD1, CREB1, EZH2, LMO2, ESR1, TP53, CHD8, CTCF, RBM22, NANOG, BCL11A, SPI1, GSPT2, AR, REST, FLI1, BRD4, FOXP1, MAZ, AATF, SMC3, POU2F2, STAG1, EED

Target gene symbol (double-evidenced CRMs): PKNOX1,DNMT3L,RRP1B,WDR4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 22

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160193, ENSG00000160199, ENSG00000160208, ENSG00000142182,

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Deatailed information for cohesin site CDBP00420764