- Basic information
- CohesinDB ID: CDBP00420767
- Locus: chr21-43682266-43682785
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE67783, ENCSR153HNT
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Cell type: K-562, Fibroblast, HSPC, RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
70% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 75%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: LCORL, XBP1, FOXA1, KDM3A, HDGF, ATF3, GLYR1, MECOM, TP63, ELF1, ZNF121, OCA2, JUN, CTCF, LMO1, SOX5, GATA6, E2F4, ZNF528, FOXA3, GATAD2A, EHMT2, TFAP2C, EED, POU2F2, ZNF263, MYCN, POU5F1, TOP2A, ZBTB48, ZSCAN5A, SAP130, DDX5, HNF4G, ERG, MYC, SMARCA4, HOMEZ, GRHL3, GABPA, DACH1, NR3C1, CEBPB, EZH2, ZHX2, SPI1, MIXL1, FLI1, NFIL3, ETV5, RUNX1, BCL6, CEBPA, ZFX, SMAD3, ZNF770, RARA, NRF1, ARNT, ZNF48, FOS, SUPT5H, CDK8, ZNF3, SETDB1, SREBF2, RBM22, SP1, HNF4A, NR4A1, REST, FOXP1, AATF, STAG1, TRP47, FOXA2, TBL1X, PAF1, ZSCAN16, WT1, YY1, RELA, JUNB, NEUROD1, SP140, ZNF143, AGO2, ZFP69B, KDM5B, NFKB1, AR, BRD4, AHR
- Target gene symbol (double-evidenced CRMs): RRP1B,PKNOX1,WDR4,DNMT3L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops