Deatailed information for cohesin site CDBP00420768


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00420768
  • Locus: chr21-43683749-43684802
  • Data sourse: GSE67783, GSE86191, GSE101921, GSE206145-NatGen2015, ENCSR153HNT, ENCSR917QNE
  • Cell type: Fibroblast, HCT-116, HCAEC, K-562, Liver, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.933
  • Subunit: SA1,Rad21,SA2,SMC1
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 70% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "4_Tx": 79%, "5_TxWk": 18%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, NFIA, CEBPA, POU5F1, PAF1, ZFX, ZBTB48, ZSCAN5A, STAT1, ESR2, FOXA1, ERG, RELA, ZNF384, ZNF90, ETS1, MYC, RAD21, SP140, NKX2-1, GLYR1, GABPA, STAT3, TAL1, NRIP1, SUPT5H, CDK8, SP2, DNMT3B, NR3C1, KLF4, TEAD3, ETV1, NEUROG2, CREB1, TP53, ESR1, MED26, ZNF334, ZNF652, JUN, RBM22, CTCF, SPI1, FLI1, SMC1, ZIM3, AHR
  • Target gene symbol (double-evidenced CRMs): PKNOX1,RRP1B,WDR4,DNMT3L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 20
  • Number of somatic mutations (non-coding): 20
  • Related genes and loops

eachgene