- Basic information
- CohesinDB ID: CDBP00420770
- Locus: chr21-43691074-43692529
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, ENCSR153HNT, GSE116344
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Cell type: RPE, Fibroblast, RH4, HCT-116, K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
70% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"4_Tx": 82%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, FOSL1, NME2, XBP1, RBFOX2, LEO1, HDGF, ZNF90, ATF3, NFIC, CBFB, GLYR1, TP63, JMJD1C, TEAD1, BCLAF1, RBM39, ESR1, MLL, TP73, CTCF, JUN, GATA6, TEAD4, TFAP2C, JARID2, GLIS1, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, RUNX1T1, ZMYND11, ZBTB48, ZSCAN5A, ERG, OGG1, ETS1, MYC, SMARCA4, GRHL3, STAT3, APC, PRDM14, DNMT3B, CEBPB, SRSF3, ZNF85, KMT2A, EZH2, SPI1, MXD3, FLI1, RUNX1, SMC1A, CEBPA, SIN3A, ZFX, TET2, ERG3, RARA, TAF15, NFIB, ARNT, NRF1, ZNF48, PRDM9, NCAPH2, SUPT5H, FOS, CHD1, MED1, TEAD3, CEBPD, SREBF2, STAT5A, RBM22, MAFK, BCL11A, HNF4A, REST, FOXP1, AATF, SMC3, STAG1, TRP47, PPARG, FOXA2, ZNF316, EBF1, AGO1, PAF1, ZNF600, WT1, ZBTB33, HOXB13, ZKSCAN1, YY1, RELA, NEUROD1, JUNB, SP140, TCF4, BHLHE22, TAL1, MAX, AGO2, MTA1, HAND2, PLAG1, CEBPG, NR2F1, KDM5B, ZNF334, NFKB1, AR, TAF1, RXR, EGR1, HEXIM1, TFIIIC, HSF1, MYNN, ZBTB26, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): PKNOX1,RRP1B,DNMT3L,WDR4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 0
- Related genes and loops