- Basic information
- CohesinDB ID: CDBP00420776
- Locus: chr21-43701896-43705438
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE116868, GSE105028, GSE165895, ENCSR917QNE, GSE67783, ENCSR000BKV, GSE86191, GSE206145-NatGen2015, ENCSR000EEG, ENCSR338DUC, GSE98367, ENCSR000BLS, GSE206145, ENCSR167MTG, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE50893
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Cell type: RPE, GM2630, H1-hESC, Fibroblast, HCT-116, Macrophage, Hep-G2, MB157, HuCC-T1, HSPC, K-562, Liver, HFFc6, GM18486, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.833
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
70% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"7_Enh": 29%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, TRIM25, NME2, FOXA1, HLF, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, THAP1, ZBTB44, MORC2, SFPQ, TEAD1, ZNF121, LMO2, OCA2, MED26, HDAC8, ZNF507, ARID5B, E4F1, SOX5, E2F4, DEK, ZNF528, RFX3, KMT2B, GATAD2A, NANOG, ZNF263, POU5F1, TOP2A, CTBP1, ZMYND11, DUX4, STAT1, SAP130, ERG, NFKB2, SMARCA4, RFX1, UBN1, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, BMPR1A, GABPB1, ZHX2, MIXL1, KLF17, GATA2, MXD3, SIX2, FLI1, DRAP1, MXI1, HCFC1, RUNX1, CEBPA, NKX2-2, HDAC1, TET2, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, ZXDC, SOX11, FOXM1, SP2, SMARCB1, TERF1, PIAS1, NR1H2, C11orf30, MBD1, GSPT2, IKZF5, ARID2, RBM25, AFF1, MBD2, ELL2, ETV4, NFATC3, CBX3, CREM, CHD2, PAF1, NFATC1, SS18, ZSCAN16, WT1, MEF2C, NEUROD1, JUNB, MCM3, TCF4, ZFP36, PLAG1, KLF4, BCL11B, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, ZBTB26, NCOR1, SCRT1, ILF3, ADNP, ZNF316, FOSL1, SMARCA2, XBP1, HNF1A, KDM4B, PBX2, SRSF4, ATF3, THRB, ZFP64, WDHD1, CBFB, TP63, MITF, ZNF467, JMJD1C, MAF, ELF1, RBM39, SNAI2, CTCF, JUN, TAF3, LMO1, ZBTB20, MNT, DPF2, SIX5, IRF4, ZNF423, PDX1, RBPJ, MLX, TFAP2C, MTA2, ZBTB17, ZBTB48, ZNF317, SRF, DDX5, NBN, PHB2, CHD4, ONECUT1, HOMEZ, RXRA, NKX3-1, LEF1, HNRNPH1, MIER3, VDR, NR3C1, ESRRA, KMT2A, CCAR2, TBL1XR1, ARHGAP35, GRHL2, EBF3, ZNF146, SMARCA5, NFIL3, THAP11, CTNNB1, ZBTB24, SOX13, AFF4, POU4F2, ZNF770, ARNT, NFIB, DAXX, BACH1, ZNF48, PRDM9, ZEB2, HMBOX1, PBX3, NCAPH2, HMGXB4, TEAD3, DIDO1, ZNF680, KLF9, TBX5, USF1, SP1, BCL11A, TFAP2A, NKX2-5, ATF7, ASH2L, CTBP2, PRDM6, SMC3, STAG1, MLLT1, TRP47, AGO1, MTA3, EBF1, MEIS1, MAFF, ZNF580, ZKSCAN1, BCL3, KDM1A, ZIC2, GATA3, TAL1, NRIP1, ZNF143, AGO2, MTA1, TP53, ZNF334, NFKB1, PHF5A, BRD2, KAT8, ARRB1, RNF2, BRD4, JUND, CUX1, PGR, SOX2, PATZ1, LEO1, SMAD1-5, UBTF, TFAP4, BMI1, CHD7, ZNF444, ATF4, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, ZNF217, ESR1, TP73, KLF1, ZNF260, SOX4, E2F6, TRIM24, RFX5, GTF2F1, GLIS1, POU2F2, CDK9-HEXIM1, ZSCAN5D, ZSCAN5A, ERG2, SP4, TBP, HNF4G, HOXC5, OGG1, ETS1, MYC, ARID1B, PHF21A, NKX2-1, GABPA, MCRS1, STAT3, IKZF1, DNMT3B, SRSF3, EZH2, ZNF652, SPI1, PCBP1, HDAC2, ZNF182, GATAD2B, NCOA2, ZNF554, ETV5, BCL6, SIN3A, ERG3, NFXL1, RARA, ZNF384, NFYC, ZNF35, TAF15, CREBBP, SMAD4, CBFA2T3, CDK8, ZEB1, ZMYM3, NCOA1, SREBF2, ZNF22, RBM22, MAFK, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, NCOR2, PPARG, TBL1X, GTF2B, ZNF30, ZNF574, TCF7, RELA, TARDBP, MAX, ZNF592, GFI1B, NR2F1, ZNF791, KDM5B, TCF7L2, PKNOX1, RUVBL1, MYOD1, AR, YAP1, ZNF324, HEXIM1, ZNF280D, DMAP1, AHR, FOSL2, MBD3, HMG20A, MEIS2, RBFOX2, ZFHX2, NFIC, ZNF362, PRDM1, GLYR1, ZNF736, CDX2, KLF5, TRIM28, RCOR2, HNF1B, MLL, USF2, MBD4, TCF12, EP300, BAF155, GATA6, RAD51, ZNF512B, E2F1, TEAD4, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, CDK7, ID3, RUNX1T1, HINFP, GATAD1, ARID3A, ASCL1, ZNF341, MCM5, RAD21, GRHL3, PROX1, APC, XRCC5, ZNF614, NFE2, ZNF639, ZNF750, FEZF1, TFE3, HBP1, ZNF664, IRF1, ZSCAN2, EHF, SREBF1, ZGPAT, MRTFB, ATF1, PTBP1, SMC1A, MAFG, CBX1, FIP1L1, ZFX, SMAD3, PCBP2, TWIST1, IRF2, PRPF4, NOTCH1, BRD9, RUNX2, CDK6, GATA4, ZNF184, GR, NRF1, PBX4, SUPT5H, CHD1, FOS, MED1, CEBPD, MYB, KDM6B, SCRT2, ZNF3, L3MBTL2, NIPBL, ZBTB7A, PHIP, TCF3, SKI, NELFA, ZNF283, KLF13, FOXA2, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, BRCA1, SP140, HIF1A, ZNF519, GATA1, TLE3, CEBPG, NCOA3, NR2F2, ZNF687, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, ZBTB42, CLOCK, MAZ, ZNF24
- Target gene symbol (double-evidenced CRMs): AGPAT3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 15
- Related genes and loops