Deatailed information for cohesin site CDBP00420782

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  • Basic information
  • CohesinDB ID: CDBP00420782
  • Locus: chr21-43714967-43730833
  • Data sourse: ENCSR230ZWH, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE93080, GSE67783, GSE86191, GSE101921, ENCSR806UKK, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, ENCSR895JMI, GSE118494, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, ENCSR676MJK, GSE155324, ENCSR054FKH, GSE83726, GSE126755, ENCSR748MVX, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR537EFT, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE76893, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE38395, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, GSE62063, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR153HNT, GSE68388, GSE126990
  • Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, OCI-AML-3, HSPC, CVI-hiPSC, Liver, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, THP-1, Ishikawa, GM12890, HeLa-S3, hLCL, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, RT-112, HAP1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, Neurons-H1, A-549, HCAEC, Ramos, GM19238, Neutrophil, GM18951
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 66% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.278
  • Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 70% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "7_Enh": 23%, "2_TssAFlnk": 22%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, PATZ1, PBX2, ZFHX2, HDGF, ZNF90, BMI1, NFIC, ZFP64, RUNX3, PRDM1, CBFB, MECOM, PAX5, MITF, BACH2, JMJD1C, ZNF629, ELF1, BCLAF1, ESR1, MLL, USF2, CTCF, JUN, TCF12, SND1, EP300, ZBTB20, DPF2, TRIM24, IRF4, RAD51, GTF2F1, RBPJ, EED, TFAP2C, GLIS1, POU2F2, ZSCAN5D, ZNF263, MYCN, BRD3, ID3, MTA2, ZBTB17, ZBTB48, ZSCAN5A, ZNF563, NBN, ARID3A, CHD4, PBX1, ZNF341, MYC, IKZF1, TERF2, CD74, ZNF639, ZNF667, VDR, NR3C1, CEBPB, KMT2A, CREB1, ZHX2, SPI1, MIXL1, ZNF257, HDAC2, GATA2, GATAD2B, FLI1, RELB, ETV5, RUNX1, BCL6, CEBPA, EZH2phosphoT487, ZFX, ZNF534, SMAD3, TRIM22, PRDM10, MEF2A, CREBBP, NOTCH1, OSR2, ZNF184, BACH1, ATF2, ZEB2, ETV6, FOXM1, PBX3, FOS, CDK8, MED1, TEAD3, ZEB1, TERF1, MYB, HIF2A, MAFK, BCL11A, SP1, NIPBL, ARID2, ATF7, ASH2L, PHIP, BCOR, TCF3, NCOR2, MLLT1, STAG1, NFATC3, MEF2B, PPARG, ZNF207, MTA3, EBF1, CREM, SS18, E2F8, ZBED1, WT1, GTF2B, ZBTB33, MEF2C, CDK9, YY1, RELA, TARDBP, JUNB, SP140, ZIC2, SKIL, TCF4, BHLHE22, BATF, MAX, ZNF143, GATA1, PLAG1, SP7, NR2F1, NEUROG2, TP53, PKNOX1, MED, ZNF334, MYOD1, EGR2, TBX21, BHLHE40, ZBTB42, EGR1, RB1, ZBTB26, NCOR1, RNF2, IKZF2, BRD4, JUND, MAZ, ZSCAN23, ZNF24, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): PDXK,HSF2BP,CBS,CSTB,NDUFV3,AGPAT3,RRP1,PKNOX1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 203
  • Number of somatic mutations (non-coding): 76
  • Related genes and loops
  • Related gene: ENSG00000160194, ENSG00000160199, ENSG00000160200, ENSG00000160207, ENSG00000160209, ENSG00000160213, ENSG00000160214, ENSG00000160216,
  • Related loop: chr21:42892194-42894528~~chr21:43717961-43720857, chr21:43025000-43050000~~chr21:43725000-43750000, chr21:43175000-43200000~~chr21:43725000-43750000, chr21:43350000-43375000~~chr21:43700000-43725000, chr21:43350000-43375000~~chr21:43725000-43750000, chr21:43575000-43600000~~chr21:43725000-43750000, chr21:43700000-43725000~~chr21:43925000-43950000, chr21:43717830-43720923~~chr21:43788650-43790245, chr21:43718134-43720810~~chr21:43788562-43790300, chr21:43727794-43729810~~chr21:43775194-43777378, chr21:43727966-43729871~~chr21:43788671-43790700, chr21:6550000-6575000~~chr21:43725000-43750000,
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