- Basic information
- CohesinDB ID: CDBP00420799
- Locus: chr21-43846899-43848050
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Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
79% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 61%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, ZNF394, POU2F2, CHD8, SMC1A, TBL1X, MYCN, ZNF697, ZNF426, ZFX, XBP1, WT1, ZBTB48, STAT1, ZNF101, TET2, ZBTB33, ZNF654, YY1, RELA, ASCL1, ZNF341, ZBTB8A, MYC, ZFP64, SP140, GRHL3, HIF1A, PRDM12, ZNF781, SMC3, ZNF518A, ZNF189, MAX, ZNF143, NCOA3, TEAD1, TRIM28, ZNF558, ZBTB11, SNAI2, ZNF3, OCA2, ZC3H11A, SETDB1, ZNF140, CTCF, ZNF577, GSPT2, ZNF664, AR, REST, E2F6, EGLN2, HSF1, BRD4, MAZ, ZNF623, NCOA2, ZNF555, ZNF34, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): TSPEAR,AGPAT3,CFAP410,PFKL,DNMT3L,TRAPPC10
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000160216,
ENSG00000160218,
ENSG00000142182,
ENSG00000141959,
ENSG00000160226,
ENSG00000175894,
- Related loop:
chr21:43175000-43200000~~chr21:43850000-43875000,
chr21:43300000-43325000~~chr21:43850000-43875000,
chr21:43750000-43775000~~chr21:43850000-43875000,
chr21:43825000-43850000~~chr21:43925000-43950000,
chr21:43825000-43850000~~chr21:43950000-43975000,
chr21:43825000-43850000~~chr21:44075000-44100000,
chr21:43825000-43850000~~chr21:44250000-44275000,
chr21:43825000-43850000~~chr21:44275000-44300000,
chr21:43825000-43850000~~chr21:44300000-44325000,
chr21:43825000-43850000~~chr21:44475000-44500000,
chr21:43850000-43875000~~chr21:43975000-44000000,
chr21:43850000-43875000~~chr21:44000000-44025000,
chr21:43850000-43875000~~chr21:44075000-44100000,
chr21:43850000-43875000~~chr21:44250000-44275000,
chr21:5125000-5150000~~chr21:43825000-43850000,