- Basic information
- CohesinDB ID: CDBP00420807
- Locus: chr21-43874006-43875186
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Data sourse: GSE86191, GSE126634, GSE152721, ENCSR153HNT, GSE116344
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Cell type: K-562, RH4, HCT-116, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
79% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 66%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, SOX2, XBP1, FOXA1, RBFOX2, TFAP4, ATF3, NFIC, RUNX3, CBFB, PAX5, TP63, RBM39, SNAI2, ETV1, LMO2, ESR1, CTCF, TCF12, JUN, TRIM24, RBPJ, EED, POU2F2, CHD8, POU5F1, ZNF263, MYCN, KDM4C, RUNX1T1, ZBTB48, STAT1, ERG, MYC, RAD21, GRHL3, GABPA, DACH1, CEBPB, EZH2, GABPB1, SPI1, IRF1, INTS13, GATA2, FLI1, RUNX1, SMC1A, BCL6, CEBPA, ZFX, TET2, CREBBP, ZNF184, ARNT, SUPT5H, CHD1, CDK8, TEAD3, MYB, ZNF3, C11orf30, EVI1, RBM22, BCL11A, HNRNPLL, FOXP1, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, NFATC1, WT1, FOXF1, ZBTB33, KDM1A, YY1, RELA, TARDBP, JUNB, AHR, SP140, BATF, TAL1, MAX, AGO2, PLAG1, NCOA3, NR2F1, MYOD1, AR, EGR1, HSF1, BRD4, JUND, CLOCK, MAZ, ZNF440, ZNF316
- Target gene symbol (double-evidenced CRMs): AGPAT3,TRAPPC10,DNMT3L,PDXK,CSTB
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 7
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160209,
ENSG00000160213,
ENSG00000160216,
ENSG00000160218,
ENSG00000142182,
- Related loop:
chr21:43175000-43200000~~chr21:43850000-43875000,
chr21:43175000-43200000~~chr21:43875000-43900000,
chr21:43300000-43325000~~chr21:43850000-43875000,
chr21:43350000-43375000~~chr21:43875000-43900000,
chr21:43750000-43775000~~chr21:43850000-43875000,
chr21:43750000-43775000~~chr21:43875000-43900000,
chr21:43850000-43875000~~chr21:43975000-44000000,
chr21:43850000-43875000~~chr21:44000000-44025000,
chr21:43850000-43875000~~chr21:44075000-44100000,
chr21:43850000-43875000~~chr21:44250000-44275000,
chr21:43875000-43900000~~chr21:44250000-44275000,