- Basic information
- CohesinDB ID: CDBP00420809
- Locus: chr21-43876860-43877126
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Data sourse: GSE206145-GSE177045, GSE67783, ENCSR153HNT
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Cell type: K-562, MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
79% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 81%,
"15_Quies": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: HDAC2, SIX2, OSR2, ZFX, PBX2, HIF1A, BRD4, ESR1, GTF2B, FEZF1, ZSCAN16, ZNF528, ZNF189, CTCF, RBM22, PRDM10
- Target gene symbol (double-evidenced CRMs): CSTB,AGPAT3,PDXK,DNMT3L
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160209,
ENSG00000160213,
ENSG00000160216,
ENSG00000142182,
- Related loop:
chr21:43175000-43200000~~chr21:43850000-43875000,
chr21:43175000-43200000~~chr21:43875000-43900000,
chr21:43300000-43325000~~chr21:43850000-43875000,
chr21:43350000-43375000~~chr21:43875000-43900000,
chr21:43750000-43775000~~chr21:43850000-43875000,
chr21:43750000-43775000~~chr21:43875000-43900000,
chr21:43850000-43875000~~chr21:43975000-44000000,
chr21:43850000-43875000~~chr21:44000000-44025000,
chr21:43850000-43875000~~chr21:44075000-44100000,
chr21:43850000-43875000~~chr21:44250000-44275000,
chr21:43875000-43900000~~chr21:44250000-44275000,