Deatailed information for cohesin site CDBP00420817

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  • Basic information
  • CohesinDB ID: CDBP00420817
  • Locus: chr21-43895698-43896321
  • Data sourse: GSE67783, ENCSR153HNT, GSE86191
  • Cell type: K-562, HCT-116, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 79% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 66%, "15_Quies": 25%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOSL1, MEIS2, XBP1, FOXA1, PBX2, UBTF, MLL4, HDGF, ATF3, NFIC, ZNF362, ZBTB5, RUNX3, PRDM1, CBFB, ZNF189, SMARCE1, PAX5, MECOM, MITF, MAF, KLF5, ELF1, TRIM28, BCLAF1, RBM39, ETV1, LMO2, ESR1, OCA2, CTCF, JUN, TCF12, EP300, E4F1, MNT, GATA6, DPF2, E2F6, TRIM24, IRF4, ZNF407, SOX6, E2F4, SMC1, TEAD4, EHMT2, RBPJ, EED, POU2F2, CHD8, TOP2A, ID3, RUNX1T1, CTBP1, MTA2, ZBTB17, KDM4C, ZSCAN5A, STAT1, DUX4, ASH1L, SRF, NBN, TBP, ERG, MIER1, SMARCC2, NFKB2, MYC, ETS1, SMARCA4, ZNF341, ARID1B, RAD21, DNMT1, ONECUT1, PROX1, NKX2-1, FOXK2, BATF3, GABPA, STAT3, XRCC5, APC, IKZF1, LEF1, NFE2, TERF2, RCOR1, NFRKB, CEBPB, KMT2A, GABPB1, ELF4, HES1, SPI1, HDAC2, GATA2, ZSCAN29, FLI1, SMARCA5, ZNF554, ATF1, ETV5, CC2D1A, RUNX1, MAFG, SMC1A, HDAC1, EZH2phosphoT487, CEBPA, BCL6, ZFX, NFXL1, PRDM10, ZBTB2, CREBBP, IRF2, ZNF384, BRD9, GATA4, ZNF184, ARNT, HMGB2, ZEB2, HMBOX1, ETV6, FOXM1, SUPT5H, CDK8, FOS, CHD1, ZEB1, TERF1, MYB, ZNF680, C11orf30, L3MBTL2, SETDB1, TBX5, EVI1, ZNF22, RBM22, BCL11A, NR4A1, NKX2-5, ZBTB7A, ATF7, ASH2L, HNRNPLL, AFF1, BCOR, SMC3, ILK, MLLT1, STAG1, NFATC3, MEF2B, PPARG, CBX3, MTA3, EBF1, CREM, RBBP5, E2F8, ZNF600, FOXA2, GTF2B, NFATC1, WT1, ZBTB33, CREB3L1, YY1, RELA, JUNB, NEUROD1, ZFP36, HIF1A, BATF, TAL1, MAX, NRIP1, ZNF143, GATA1, ZNF592, NCOA3, NR2F2, GFI1B, ZNF512, NR2F1, TCF7L2, TP53, PKNOX1, NFKB1, BRD2, TBX21, BHLHE40, PAX3-FOXO1, AR, TAF1, PTRF, ZBTB40, YAP1, HSF1, RNF2, NCOR1, BRD4, ILF3, JUND, MAZ, ZNF24, ZNF316
  • Target gene symbol (double-evidenced CRMs): AGPAT3,CSTB,PDXK,DNMT3L
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 8
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000160209, ENSG00000160213, ENSG00000160216, ENSG00000142182,
  • Related loop: chr21:43000000-43025000~~chr21:43900000-43925000, chr21:43175000-43200000~~chr21:43875000-43900000, chr21:43350000-43375000~~chr21:43875000-43900000, chr21:43350000-43375000~~chr21:43900000-43925000, chr21:43750000-43775000~~chr21:43875000-43900000, chr21:43800000-43825000~~chr21:43900000-43925000, chr21:43875000-43900000~~chr21:44250000-44275000, chr21:43900000-43925000~~chr21:44250000-44275000, chr21:43900000-43925000~~chr21:44425000-44450000, chr21:43900000-43925000~~chr21:44475000-44500000, chr21:43900000-43925000~~chr21:45400000-45425000,
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