- Basic information
- CohesinDB ID: CDBP00420827
- Locus: chr21-43914602-43914828
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Data sourse: GSE67783, ENCSR153HNT
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Cell type: K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
79% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 64%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PATZ1, PBX2, ZNF90, ZFP64, RUNX3, ZBTB44, IKZF3, ZNF189, PAX5, ZNF736, ZNF629, KLF5, TRIM28, RBM39, KLF10, TP73, JUN, CTCF, DPF2, ZNF423, E2F1, GLIS1, CHD8, MYCN, ZBTB48, ZBTB21, ZNF341, ZBTB8A, RXRA, ZNF614, IKZF1, LEF1, NR2F6, CEBPB, CREB1, GATA2, FLI1, MRTFB, ZNF554, ATF1, RUNX1, BCL6, SIN3A, ZFX, ZNF770, SMARCC1, MEF2A, RARA, ZNF184, ARNT, ZNF48, ZEB2, CDK8, MYB, SCRT2, ZMYM3, EVI1, SP1, BCL11A, ZBTB7A, HOXA9, PHIP, TCF3, BCOR, PRDM6, STAG1, MEF2B, CBX3, CREM, RBBP5, SS18, WT1, ZBTB33, MEF2C, TCF7, YY1, RELA, SP140, ZIC2, MAX, GATA1, NR2F2, TCF7L2, NR2F1, NEUROG2, TP53, BRD2, HSF1, IKZF2, BRD4, SCRT1, JUND, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): COL18A1,TRPM2,RRP1,DNMT3L,PKNOX1,TSPEAR,AGPAT3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000160199,
ENSG00000160214,
ENSG00000160216,
ENSG00000142182,
ENSG00000142185,
ENSG00000175894,
ENSG00000182871,
- Related loop:
chr21:43000000-43025000~~chr21:43900000-43925000,
chr21:43350000-43375000~~chr21:43900000-43925000,
chr21:43800000-43825000~~chr21:43900000-43925000,
chr21:43810123-43811942~~chr21:43917618-43918968,
chr21:43864707-43867527~~chr21:43916051-43918979,
chr21:43900000-43925000~~chr21:44250000-44275000,
chr21:43900000-43925000~~chr21:44425000-44450000,
chr21:43900000-43925000~~chr21:44475000-44500000,
chr21:43900000-43925000~~chr21:45400000-45425000,