- Basic information
- CohesinDB ID: CDBP00420828
- Locus: chr21-43915079-43915725
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Data sourse: GSE67783, ENCSR153HNT, GSE86191
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Cell type: K-562, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
79% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 67%,
"15_Quies": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: BCOR, ESR1
- Target gene symbol (double-evidenced CRMs): TRPM2,PKNOX1,COL18A1,TSPEAR,AGPAT3,DNMT3L,RRP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 21
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000160199,
ENSG00000160214,
ENSG00000160216,
ENSG00000142182,
ENSG00000142185,
ENSG00000175894,
ENSG00000182871,
- Related loop:
chr21:43000000-43025000~~chr21:43900000-43925000,
chr21:43350000-43375000~~chr21:43900000-43925000,
chr21:43800000-43825000~~chr21:43900000-43925000,
chr21:43810123-43811942~~chr21:43917618-43918968,
chr21:43864707-43867527~~chr21:43916051-43918979,
chr21:43900000-43925000~~chr21:44250000-44275000,
chr21:43900000-43925000~~chr21:44425000-44450000,
chr21:43900000-43925000~~chr21:44475000-44500000,
chr21:43900000-43925000~~chr21:45400000-45425000,