Deatailed information for cohesin site CDBP00420829

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  • Basic information
  • CohesinDB ID: CDBP00420829
  • Locus: chr21-43916632-43919024
  • Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000FAD, GSE72082, ENCSR000BSB, GSE116868, ENCSR000EGW, GSE105028, GSE121355, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE138405, GSE86191, GSE76893, GSE51234, GSE206145-NatGen2015, ENCSR703TNG, GSE94872, ENCSR000EEG, ENCSR879KXD, ENCSR000BLS, GSE206145, ENCSR000BMY, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, GSE155324, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE50893, ENCSR000ECS, GSE38411
  • Cell type: GM10847, GM2610, GM19240, Liver, GP5d, HuCC-T1, B-cell, H9-hESC, GM2630, RPE, Fibroblast, GM12890, HeLa-S3, GM2255, BCBL-1, K-562, GM18486, GM18526, H1-hESC, SNYDER, MB157, Lymphoblast, GM12878, GM12891, GM2588, GM19239, GM19193, GM19099, MCF-7, GM12892, Hela-Kyoto, HCT-116, Hep-G2, A-549, HUVEC, GM19238, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 21% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.589
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: CTCF CTCF motif: True
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 79% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "5_TxWk": 31%, "7_Enh": 23%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, PGR, ZNF426, NME2, PATZ1, HLF, SUZ12, RBFOX2, PBX2, UBTF, RXRB, ZFHX2, HNRNPK, HDGF, ZNF90, ATF3, NFIC, INSM2, BMI1, CTCFL, RUNX3, PRDM1, ZNF444, ATF4, CBFB, ZNF189, SMARCE1, PAX5, TP63, ZSCAN4, ZNF320, CDC5L, MAF, RLF, JMJD1C, ELF1, BCLAF1, TRIM28, RBM39, SNAI2, NFE2L2, ZNF629, SMAD5, LMO2, ESR1, OCA2, TP73, HDAC8, USF2, ZFP91, CTCF, SND1, JUN, TCF12, E4F1, KLF1, MNT, DPF2, E2F6, DMAP1, IRF4, TRIM24, GLI4, CREB3, E2F4, RAD51, ZNF410, ZNF423, ZNF776, TEAD4, GTF2F1, GATAD2A, RBPJ, EED, TFAP2C, GLIS1, YBX1, POU2F2, ZSCAN5D, POU5F1, MYCN, CDK7, ID3, TOP2A, CTBP1, MTA2, RUNX1T1, ZBTB48, ZNF263, STAT1, ZBTB17, ZSCAN21, SRF, GATAD1, DDX5, NBN, ARID3A, PHB2, ERG2, TBP, ZNF300, ERG, SAP130, ZBTB21, MIER1, ZNF341, OGG1, MYC, EZH1, SMARCA4, RFX1, ARID1B, FOXP2, ZNF597, GRHL3, RAD21, RXRA, NKX2-1, FOXK2, GABPA, STAT3, APC, ZNF8, XRCC5, ZNF398, IKZF1, NFE2, RCOR1, ZNF639, NR2F6, ARNTL, DNMT3B, CEBPB, SRSF3, STAT5B, KMT2A, CREB1, EZH2, FEZF1, GABPB1, PHF8, SPI1, IRF1, ZNF257, PCBP1, HDAC2, KLF17, SSRP1, GATA2, GATAD2B, MXD3, ZSCAN29, ZNF146, FLI1, HCFC1, MXI1, SMARCA5, ZNF490, RELB, EP400, NFYB, ZNF76, NFIL3, ATF1, PTBP1, RUNX1, SMC1A, BCL6, HDAC1, CBX1, ZNF707, CEBPA, SOX13, ZFX, ZNF534, NKX2-2, PCBP2, ZNF473, ERG3, TRIM22, TWIST1, PRDM10, ZNF18, MEF2A, IRF2, ZNF384, PRPF4, ZBTB2, NOTCH1, BRD9, RUNX2, RARA, OSR2, ZNF184, ARNT, BACH1, ATF2, PRDM9, ZEB2, NFYA, SMAD4, FOXM1, PBX3, MAFB, SUPT5H, FOS, MED1, GMEB1, ZEB1, PML, KDM6B, MYB, TERF1, TEAD3, SMAD1, VEZF1, ZMYM3, U2AF1, NCOA1, L3MBTL2, C11orf30, STAT5A, RBM22, MAFK, BCL11A, SP1, NIPBL, HNF4A, REST, ZBTB7A, ATF7, ASH2L, HNRNPLL, AFF1, BCOR, TCF3, AATF, SMC3, MLLT1, STAG1, ZNF239, NFATC3, TRP47, MEF2B, CBX3, MTA3, RBBP5, CREM, EBF1, E2F8, ZNF600, HDAC6, GTF2B, ZBED1, CHD2, WT1, FOXF1, NFATC1, MAFF, ZBTB33, CDK9, ZKSCAN1, BCL3, KDM1A, YY1, RELA, TARDBP, ZNF148, AHR, SP140, ZFP36, SKIL, HIF1A, ZIC2, GATA3, BATF, MGA, TAL1, MAX, ZNF143, GATA1, AGO2, PLAG1, CEBPG, ZNF592, BCL11B, SP7, NCOA3, ZNF512, NR2F1, ZNF791, KDM5B, ZNF687, PKNOX1, IRF5, TP53, ZNF334, BCL6B, EGR2, TBX21, BHLHE40, AR, ZNF445, TAF1, ARID4B, ZBTB40, RXR, ZNF324, ZBTB42, HEXIM1, RB1, EGR1, MYNN, RNF2, IKZF2, BRD4, ILF3, HSF1, ZBTB26, TFIIIC, MAZ, JUND, ZSCAN23, ZNF24, ZNF316
  • Target gene symbol (double-evidenced CRMs): AGPAT3,RRP1,TSPEAR,PKNOX1,DNMT3L,COL18A1,TRPM2
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 66
  • Number of somatic mutations (non-coding): 22
  • Related genes and loops
  • Related gene: ENSG00000160199, ENSG00000160214, ENSG00000160216, ENSG00000142182, ENSG00000142185, ENSG00000175894, ENSG00000182871,
  • Related loop: chr21:43000000-43025000~~chr21:43900000-43925000, chr21:43350000-43375000~~chr21:43900000-43925000, chr21:43800000-43825000~~chr21:43900000-43925000, chr21:43810123-43811942~~chr21:43917618-43918968, chr21:43864707-43867527~~chr21:43916051-43918979, chr21:43900000-43925000~~chr21:44250000-44275000, chr21:43900000-43925000~~chr21:44425000-44450000, chr21:43900000-43925000~~chr21:44475000-44500000, chr21:43900000-43925000~~chr21:45400000-45425000,
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