Browse_each

Basic information

CohesinDB ID: CDBP00420836

Locus: chr21-43949301-43950152

Data sourse: GSE86191, ENCSR153HNT, ENCSR000BKV

Cell type: K-562, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 79% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 36%, "8_ZNF/Rpts": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, TRIM25, FOXA1, RXRB, MLL4, KDM3A, ZBTB7B, HDGF, THAP1, ZBTB44, IKZF3, MORC2, PAX5, ZNF320, TEAD1, ZNF121, LMO2, OCA2, HDAC8, ZNF561, E4F1, ARID5B, SOX5, DEK, E2F4, ZNF528, RFX3, GATAD2A, JARID2, NANOG, POU5F1, ZNF263, BRD3, TOP2A, CTBP1, ERF, ZMYND11, STAT1, SAP130, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, RFX1, FOXK2, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, KLF17, GATA2, ZNF644, MXD3, SIX2, FLI1, HCFC1, MXI1, NR2C2, DRAP1, RELB, HCFC1R1, EP400, RUVBL2, RUNX1, HDAC1, NKX2-2, CEBPA, CRY1, IRF3, TET2, ZNF654, SP5, TRIM22, SMARCC1, PRDM10, ZBTB2, TFDP1, ZBTB10, ELK1, ATF2, FOXM1, GMEB1, TERF1, PML, PIAS1, SMAD1, ZNF331, C11orf30, EVI1, MBD1, STAT5A, GSPT2, IKZF5, RBM25, MBD2, ELL2, ETV4, NFATC3, CBFA2T2, MEF2B, CBX3, ZNF207, CREM, CHD2, PAF1, NFATC1, ZSCAN16, WT1, MEF2C, NEUROD1, JUNB, ZFP36, ZNF311, BATF, PLAG1, KLF4, BCL11B, ZNF281, ZBTB6, MED, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, NCOR1, ZBTB26, SCRT1, ILF3, ADNP, ZNF316, FOSL1, ZNF660, XBP1, KDM4B, PBX2, TSC22D4, ATF3, THRB, ZFP64, RUNX3, CBFB, DPF1, TP63, ZSCAN4, MITF, BACH2, ZNF467, MAF, JMJD1C, ELF1, ZNF573, RBM39, SNAI2, SMAD5, CTCF, JUN, MNT, LMO1, DPF2, RYBP, IRF4, DDX20, ZNF423, ZNF280A, PDX1, TFAP2C, RBPJ, MLX, YBX1, MTA2, ZSCAN21, ZBTB48, ZBTB17, NONO, SRF, DDX5, NBN, CHD4, PBX1, ONECUT1, ZNF2, HOMEZ, FOXP2, RXRA, NKX3-1, PRDM14, LEF1, TERF2, MIER3, HNRNPH1, VDR, NR3C1, ESRRA, STAT5B, KMT2A, TBL1XR1, KLF8, GRHL2, ZNF565, EBF3, SSRP1, ZNF146, SMARCA5, NFIL3, CC2D1A, THAP11, SOX13, AFF4, ZNF770, ZMIZ1, ZNF18, CEBPZ, ARNT, BACH1, DAXX, ZNF48, PRDM9, HMBOX1, ZEB2, NFYA, PBX3, NCAPH2, MAFB, ETV6, HMGXB4, TEAD3, ZXDB, TAF7, KLF9, USF1, BCL11A, SP1, ZNF479, ATF7, ASH2L, CTBP2, GLIS2, SMC3, STAG1, MLLT1, STAG2, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MAFF, ZNF580, BCL3, ZKSCAN1, KDM1A, ISL1, ZIC2, PCGF1, TAL1, NRIP1, ZNF143, AGO2, MTA1, CBX2, TP53, ZNF334, NFKB1, BRD2, PHF5A, KAT8, TBX21, EGR1, RB1, RNF2, IKZF2, BRD4, JUND, CUX1, ZSCAN23, PGR, CBX5, SOX2, PATZ1, LEO1, UBTF, TFAP4, SIN3B, CHD7, ZNF444, MXD4, ZNF189, SMARCE1, KLF6, NFE2L2, ZNF217, ESR1, SND1, KLF1, SOX9, SOX4, E2F6, TRIM24, RFX5, PRKDC, GTF2F1, GLIS1, POU2F2, ZSCAN5D, KDM4C, ZSCAN5A, HIC1, ERG2, SP4, TBP, HNF4G, OGG1, ETS1, MYC, ARID1B, NKX2-1, GABPA, STAT3, IKZF1, DNMT3B, SRSF3, EZH2, ZNF652, PHF8, SPI1, PCBP1, HDAC2, INTS13, GATAD2B, NFYB, ETV5, BCL6, SIN3A, ERG3, NFXL1, MEF2A, RARA, ZNF384, ZNF35, CREBBP, TAF15, NFYC, SMAD4, CBFA2T3, CDK8, ZEB1, ZMYM3, NCOA1, GTF3C2, RBM22, MAFK, NR4A1, HNF4A, REST, ZHX1, HNRNPLL, BCOR, FOXP1, AATF, NCOR2, CXXC4, PPARG, TBL1X, ZNF692, GTF2B, ZNF574, TCF7, RELA, TARDBP, SKIL, MAX, ZNF592, GFI1B, NR2F1, TCF7L2, KDM5B, PKNOX1, AR, ZNF445, ZNF324, HEXIM1, ZNF280D, DMAP1, AHR, FOSL2, HMG20A, ZSCAN5C, HMGN3, MEIS2, SUZ12, RBFOX2, ZFHX2, ZNF90, NFIC, ZNF362, ZBTB5, CTCFL, PRDM1, ZNF736, CDX2, ZNF629, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, USF2, TCF12, EP300, GATA6, CREB3, SOX6, RAD51, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EHMT2, EED, CHD8, BRD1, MYCN, CDK7, ID3, RUNX1T1, GATAD1, ARID3A, ASCL1, MIER1, ZNF341, EOMES, RAD21, GRHL3, XRCC5, ZNF614, NFE2, ZNF639, JMJD6, TFE3, HBP1, IRF1, SREBF1, ZGPAT, MRTFB, ZC3H11A, ATF1, PTBP1, CBX1, SMC1A, MAFG, SIRT6, FIP1L1, ZFX, ZNF534, SMAD3, TWIST1, IRF2, PRPF4, NOTCH1, RUNX2, ZSCAN30, GATA4, CDK6, ZNF184, NRF1, NR2C1, CHD1, FOS, SUPT5H, MED1, KDM6B, CEBPD, SCRT2, MYB, VEZF1, ZNF3, L3MBTL2, SETDB1, KLF16, NIPBL, ZBTB7A, PHIP, TCF3, SKI, PAX7, ZNF283, FOXA2, RBBP5, E2F8, ZNF600, MIER2, ZBTB33, CDK9, HOXB13, YY1, BRCA1, SP140, HIF1A, OTX2, GATA1, HAND2, CEBPG, SP7, NCOA3, NR2F2, ZNF687, NFKBIZ, BHLHE40, TAF1, ZNF579, ZBTB40, MYNN, CLOCK, MAZ, ZNF24

Target gene symbol (double-evidenced CRMs): AGPAT3,PFKL,RRP1,TRAPPC10,CFAP410,UBE2G2,PDXK,RRP1B,DNMT3L,PDE9A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 30

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000160191, ENSG00000160208, ENSG00000160209, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000184787,

eachgene

Deatailed information for cohesin site CDBP00420836