- Basic information
- CohesinDB ID: CDBP00420840
- Locus: chr21-43960797-43961167
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Data sourse: GSE67783, ENCSR153HNT
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Cell type: K-562, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
79% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 57%,
"5_TxWk": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, CDK7, NFATC1, ZFX, ZBTB48, ZBTB33, BCL3, CREBBP, PBX1, NOTCH1, NKX2-1, GATA3, GABPA, PBX3, MAF, KMT2A, MYB, RBM22, SND1, SPI1, BRD4, TCF3, RBPJ
- Target gene symbol (double-evidenced CRMs): PFKL,AGPAT3,PDE9A,TRAPPC10,RRP1,DNMT3L,UBE2G2,CFAP410
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000160191,
ENSG00000160214,
ENSG00000160216,
ENSG00000160218,
ENSG00000142182,
ENSG00000141959,
ENSG00000160226,
ENSG00000184787,
- Related loop:
chr21:42650000-42675000~~chr21:43950000-43975000,
chr21:43175000-43200000~~chr21:43950000-43975000,
chr21:43300000-43325000~~chr21:43950000-43975000,
chr21:43350000-43375000~~chr21:43950000-43975000,
chr21:43800000-43825000~~chr21:43950000-43975000,
chr21:43825000-43850000~~chr21:43950000-43975000,
chr21:43950000-43975000~~chr21:44050000-44075000,
chr21:43950000-43975000~~chr21:44250000-44275000,
chr21:43950000-43975000~~chr21:44275000-44300000,
chr21:43950000-43975000~~chr21:44300000-44325000,
chr21:43950000-43975000~~chr21:44750000-44775000,