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Basic information

CohesinDB ID: CDBP00420855

Locus: chr21-43997663-43998474

Data sourse: GSE67783, ENCSR153HNT, GSE68388

Cell type: K-562, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 79% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 53%, "14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NFIA, FOSL1, MYCN, EZH2phosphoT487, SIN3A, ZFX, XBP1, WT1, SMAD3, FOXA1, ERG3, BCL3, PRDM10, HOXC5, NFIC, NFIB, DAXX, ZEB2, PBX3, GATA1, FOS, CBX2, TP53, FEZF1, JUN, CTCF, ZNF507, BCL11A, AR, ZNF528, ZNF24, STAG1

Target gene symbol (double-evidenced CRMs): PFKL,TRAPPC10,PKNOX1,RRP1,DNMT3L,CFAP410,AGPAT3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000142182, ENSG00000141959, ENSG00000160226,

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Deatailed information for cohesin site CDBP00420855