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Basic information

CohesinDB ID: CDBP00420875

Locus: chr21-44037935-44038524

Data sourse: GSE206145-NatGen2015, GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 80%, "5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, POU2F2, ZNF283, TRIM25, FOXA2, MYCN, TBL1X, ZFX, ZNF600, XBP1, ZBTB48, ZSCAN5A, WT1, TET2, ZBTB33, LEO1, YY1, RELA, ETS1, KAT2B, SP140, GRHL3, HIF1A, TFDP1, STAT3, APC, XRCC5, SUPT5H, AGO2, SMARCB1, DNMT3B, ZNF143, CHD1, ARNTL, TERF1, KDM5B, ZNF3, EZH2, OCA2, SMAD5, ESR1, GRHL2, CTCF, ZHX2, RBM22, AR, RXR, FLI1, HSF1, BRD4, MAZ, AATF, SMC3, NCOR2, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): DNMT3L,TRAPPC10,PKNOX1,LRRC3,AGPAT3,PFKL,CFAP410

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160216, ENSG00000160218, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000160233,

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Deatailed information for cohesin site CDBP00420875