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Basic information

CohesinDB ID: CDBP00420881

Locus: chr21-44046465-44047576

Data sourse: GSE67783, GSE86191, GSE98367, GSE206145-NatGen2015, GSE120943, ENCSR153HNT

Cell type: Fibroblast, HCT-116, Monocytes, K-562, HSPC, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 57%, "4_Tx": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GRHL3, ESR1

Target gene symbol (double-evidenced CRMs): LRRC3,DNMT3L,PFKL,TRAPPC10,AGPAT3,CFAP410,PKNOX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 18

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160216, ENSG00000160218, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000160233,

eachgene

Deatailed information for cohesin site CDBP00420881