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Basic information

CohesinDB ID: CDBP00420884

Locus: chr21-44051500-44052149

Data sourse: ENCSR230ZWH, GSE67783, GSE86191, ENCSR153HNT, ENCSR917QNE

Cell type: K-562, Liver, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 38%, "4_Tx": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, TRIM25, PGR, XBP1, FOXA1, SUZ12, PRDM1, ZNF189, ZNF629, ETV1, RBM39, ESR1, OCA2, JUN, CTCF, BAF155, LMO1, ZNF528, PDX1, TFAP2C, GLIS1, POU2F2, CHD8, BRD1, POU5F1, ZNF263, MYCN, ZBTB17, ZBTB48, ERG, PBX1, ONECUT1, MYC, SMARCA4, GRHL3, NKX2-1, GABPA, STAT3, XRCC5, NKX3-1, IKZF1, ZNF639, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, EZH2, SPI1, GATA2, RUNX1, BCL6, NKX2-2, ZFX, TET2, NSD2, RUNX2, ARNT, ATF2, ETV6, MAFB, SUPT5H, SMARCB1, CHD1, MED1, MYB, PIAS1, ZNF3, RBM22, GSPT2, HNF4A, ATF7, ASH2L, PHIP, TCF3, FOXP1, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, TBL1X, EBF1, ZNF600, ZSCAN16, WT1, FOXF1, HOXB13, YY1, RELA, SP140, ZIC2, GATA3, TAL1, MAX, NRIP1, ZNF143, AGO2, SP7, NCOA3, NEUROG2, TP53, MED, MYOD1, AR, ZBTB26, BRD4, JUND, MAZ, AHR

Target gene symbol (double-evidenced CRMs): PTTG1IP,TSPEAR,PFKL,TRPM2,PKNOX1,AGPAT3,DNMT3L,GATD3A,CFAP410,RRP1,SUMO3,LRRC3,TRAPPC10,UBE2G2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255,

eachgene

Deatailed information for cohesin site CDBP00420884