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Basic information

CohesinDB ID: CDBP00420885

Locus: chr21-44058034-44059019

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 59%, "5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, ZSCAN5C, XBP1, FOXA1, LEO1, ZFHX2, ATF3, ZSCAN4, TEAD1, BCLAF1, SNAI2, SMAD5, CTCF, PAX8, E2F4, TFAP2C, EED, GLIS1, POU2F2, CHD8, MYCN, ZNF263, ZBTB48, ZSCAN5A, STAT1, ERG2, TBP, ETS1, MYC, SMARCA4, GRHL3, STAT3, XRCC5, NR3C1, CEBPB, EZH2, SPI1, RUNX1, CEBPA, ZFX, SMAD3, TET2, ERG3, ZNF384, RUNX2, ARNT, BACH1, SOX11, ETV6, SUPT5H, CHD1, TERF1, SCRT2, STAT5A, RBM22, BCL11A, FOXP1, SMC3, STAG1, TRP47, CBFA2T2, PAF1, ZNF600, WT1, CDK9, HOXB13, YY1, RELA, NEUROD1, SP140, ZIC2, HIF1A, OTX2, BATF, MAX, ZNF143, AGO2, CEBPG, NEUROG2, PKNOX1, ZNF334, EGR2, AR, NCOR1, BRD4, SCRT1, JUND, MAZ, AHR

Target gene symbol (double-evidenced CRMs): UBE2G2,PKNOX1,RRP1,CFAP410,LRRC3,PFKL,TRPM2,TSPEAR,SUMO3,DNMT3L,AGPAT3,TRAPPC10,GATD3A,PTTG1IP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 10

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255,

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Deatailed information for cohesin site CDBP00420885