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Basic information

CohesinDB ID: CDBP00420896

Locus: chr21-44074197-44074929

Data sourse: ENCSR000BTQ, ENCSR230ZWH, GSE67783, GSE72082, GSE86191, GSE111913, ENCSR153HNT, GSE83726, ENCSR703TNG, GSE25021

Cell type: MCF-7, HCT-116, RH4, RT-112, K-562, Liver, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 69%, "5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, CHD8, ZNF263, MYCN, CRY1, ZFX, XBP1, ZBTB48, WT1, FOXA1, ERG3, YY1, RELA, ATF3, MYC, CDK6, THAP1, RAD21, SP140, GRHL3, HIF1A, ARNT, XRCC5, SUPT5H, ZNF143, DNMT3B, CREB1, LMO2, ESR1, OCA2, CTCF, RBM22, AR, REST, HSF1, BRD4, CLOCK, MAZ, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): PFKL,RRP1,PKNOX1,CFAP410,TRPM2,AGPAT3,LRRC3,DNMT3L,TSPEAR,UBE2G2,SUMO3,GATD3A,PTTG1IP,TRAPPC10

Function elements

Human SNPs: .

Number of somatic mutations (coding): 20

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255,

eachgene

Deatailed information for cohesin site CDBP00420896