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Basic information

CohesinDB ID: CDBP00420902

Locus: chr21-44086043-44086366

Data sourse: GSE67783, GSE83726

Cell type: RH4, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 42%, "5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, HMGN3, NME2, XBP1, HNF1A, FOXA1, LEO1, HDGF, LYL1, ATF3, ZNF362, THAP1, RUNX3, CBFB, GLYR1, DPF1, SMARCE1, MECOM, TP63, MITF, MAF, JMJD1C, KLF5, ELF1, TEAD1, BCLAF1, RBM39, TRIM28, SNAI2, ZNF26, LMO2, ESR1, MLL, HNF1B, ZNF573, HDAC8, OCA2, USF2, CTCF, ZNF507, JUN, TCF12, ARID5B, MNT, LMO1, GATA6, DPF2, SOX4, IRF4, CREB3, RAD51, PRKDC, E2F1, TEAD4, PDX1, TFAP2C, EED, GLIS1, POU2F2, CHD8, BRD1, ZSCAN5D, MYCN, ZNF263, TOP2A, ID3, CDK7, RUNX1T1, POU5F1, ZBTB17, ZBTB48, ZSCAN5A, DUX4, DDX5, ERG2, ZNF300, ERG, PBX1, OGG1, ZNF341, ETS1, MYC, EZH1, SMARCA4, RAD21, GRHL3, RXRA, NKX2-1, PROX1, GABPA, STAT3, NKX3-1, RCOR1, DNMT3B, NFE2, CD74, ZNF750, NR3C1, CEBPB, STAT5B, KMT2A, EZH2, BMPR1A, GRHL2, SPI1, HDAC2, GATA2, INTS13, SSRP1, GATAD2B, MXD3, FLI1, NCOA2, RUNX1, CTNNB1, CBX1, BCL6, HDAC1, LDB1, CEBPA, SMC1A, SIN3A, ZFX, POU4F2, NKX2-2, CRY1, SMAD3, ZNF770, ERG3, TET2, CREBBP, ZNF384, ZXDC, NOTCH1, TAF15, RUNX2, GATA4, ARNT, NFIB, PRDM9, CBFA2T3, SUPT5H, FOS, SNRNP70, CHD1, MED1, TEAD3, PML, CEBPD, MYB, TERF1, ZEB1, ZNF3, EVI1, SREBF2, RBM22, USF1, SP1, TFAP2A, BCL11A, HNF4A, NIPBL, MAFK, ZBTB7A, HNRNPLL, CTBP2, TCF3, FOXP1, BCOR, AATF, MLLT1, STAG1, ZNF394, PAX7, SKI, TRP47, CBFA2T2, KLF13, MEF2B, FOXA2, TBL1X, CREM, EBF1, PAF1, NFATC1, ZNF600, WT1, ZBTB33, CDK9, ZNF580, HOXB13, YY1, RELA, JUNB, SP140, TCF4, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, AGO2, GATA1, CBX2, ZNF592, BCL11B, NCOA3, NR2F2, BAP1, NR2F1, TCF7L2, KDM5B, ZNF687, ZBTB6, TP53, ZNF334, NFKB1, MYOD1, EGR2, ELF3, TBX21, BHLHE40, AR, TAF1, EGR1, HEXIM1, ZBTB26, HSF1, MYNN, BRD4, JUND, SCRT1, CLOCK, MAZ, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): AGPAT3,UBE2G2,CFAP410,GATD3A,LRRC3,PFKL,PTTG1IP,DNMT3L,TRAPPC10,PKNOX1,TSPEAR,RRP1,TRPM2,COL18A1,CBS,ITGB2,POFUT2,SUMO3,ADARB1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160200, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255, ENSG00000160255, ENSG00000197381, ENSG00000186866, ENSG00000182871,

eachgene

Deatailed information for cohesin site CDBP00420902