Browse_each

Basic information

CohesinDB ID: CDBP00420905

Locus: chr21-44093882-44094111

Data sourse: GSE206145-NatGen2015, GSE86191

Cell type: Fibroblast, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 58%, "5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, CHD8, BRD1, SMC1A, ZNF263, POU5F1, MYCN, ZFX, XBP1, ZBTB48, WT1, KDM4B, HOXB13, ERG, YY1, RELA, ZNF341, ATF3, MYC, CDK6, SP140, GRHL3, HIF1A, ARNT, TP63, SUPT5H, AGO2, ZNF143, NCOA3, BAP1, NR2F1, EZH2, ZNF3, KDM5B, OCA2, ESR1, GRHL2, ZNF334, MYOD1, CTCF, RBM22, GSPT2, PAX3-FOXO1, AR, REST, HEXIM1, HSF1, BRD4, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): SUMO3,PKNOX1,UBE2G2,COL18A1,ADARB1,TRAPPC10,TRPM2,AGPAT3,TSPEAR,LRRC3,DNMT3L,PFKL,CBS,CFAP410,RRP1,PTTG1IP,POFUT2,ITGB2,GATD3A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 12

Number of somatic mutations (non-coding): 12

Related genes and loops

Related gene: ENSG00000160199, ENSG00000160200, ENSG00000160214, ENSG00000160216, ENSG00000160218, ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000160226, ENSG00000142185, ENSG00000160233, ENSG00000175894, ENSG00000184787, ENSG00000184900, ENSG00000183255, ENSG00000160255, ENSG00000197381, ENSG00000186866, ENSG00000182871,

eachgene

Deatailed information for cohesin site CDBP00420905