- Basic information
- CohesinDB ID: CDBP00420908
- Locus: chr21-44113185-44114709
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BSB, GSE116868, ENCSR000EGW, ENCSR000BLY, GSE105028, GSE103477, GSE111537, GSE131606, GSE108869, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, ENCSR000BKV, GSE67783, GSE138405, GSE86191, GSE101921, GSE206145-NatGen2015, GSE120943, GSE130135, GSE116344, GSE94872, ENCSR338DUC, GSE98367, ENCSR879KXD, ENCSR000BLS, ENCSR000ECE, ENCSR000BMY, GSE55407, ENCSR167MTG, GSE110061, GSE129526, GSE111913, GSE155324, ENCSR054FKH, ENCSR153HNT, GSE68388, GSE83726, GSE50893, GSE126755, ENCSR000ECS, GSE38411
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Cell type: MDM, RH4, GM10847, GM2610, GM19240, OCI-AML-3, HSPC, Liver, HuCC-T1, H9-hESC, GM2630, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, BCBL-1, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, Monocytes, GM18505, MB157, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, RT-112, GM19193, THP-1, GM19099, Macrophage, MCF-7, GM12892, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, HUVEC, HCAEC, GM19238, Neutrophil, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 25% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.467
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: False
- Compartment:
62% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"4_Tx": 60%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CTCF
- Target gene symbol (double-evidenced CRMs): PWP2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 72
- Number of somatic mutations (non-coding): 72
- Related genes and loops