Browse_each

Basic information

CohesinDB ID: CDBP00420923

Locus: chr21-44172520-44173627

Data sourse: ENCSR230ZWH, GSE72082, GSE116868, GSE103477, GSE25021, GSE131606, GSE115602, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, GSE67783, GSE86191, GSE101921, GSE206145-NatGen2015, GSE120943, GSE98367, GSE206145, GSE85526, ENCSR000BMY, GSE38395, GSE111913, ENCSR153HNT, GSE68388, GSE50893, GSE126755

Cell type: GM2610, Liver, HuCC-T1, B-cell, RPE, GM2630, Fibroblast, HEKn, Ishikawa, GM12890, hLCL, GM2255, K-562, GM18486, DKO, SNYDER, Monocytes, MB157, GM12878, GM12891, GM2588, RT-112, THP-1, Macrophage, MCF-7, GM12892, HCT-116, HCAEC, GM19238, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 10% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.656

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: TSS,TES

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: False

Compartment: 62% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "7_Enh": 33%, "15_Quies": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: .

Target gene symbol (double-evidenced CRMs): DNMT3L,TSPEAR,PFKL,GATD3A

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000160221, ENSG00000142182, ENSG00000141959, ENSG00000175894,

eachgene

Deatailed information for cohesin site CDBP00420923